SCHEMBL26567161

SCHEMBL26567161

CO[C@@H]1[C@H](OC(OC[C@H]2O[C@@H](n3cnc4c(=O)[nH]c(N)nc43)[C@H](O)[C@@H]2O)C(=O)O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O[C@H]1n1cnc2c(=O)[nH]c(N)nc21

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 1/20 0.62
KRAS P01116 6/20 0.61
FUT5 Q11128 1/20 0.60
NT5E P21589 1/20 0.58
P2RY6 Q15077 2/20 0.56
P2RY2 P41231 1/20 0.56
P2RY4 P51582 1/20 0.56
RNASEL Q05823 1/20 0.55
P2RX3 P56373 2/20 0.54
ENPP1 P22413 2/20 0.54
P2RY1 P47900 2/20 0.54
P2RX1 P51575 1/20 0.54
P2RY11 Q96G91 1/20 0.54
P2RX4 Q99571 1/20 0.54
TAS1R3 Q7RTX0 1/20 0.54
TAS1R1 Q7RTX1 1/20 0.54
IMPDH2 P12268 1/20 0.54
IMPDH1 P20839 1/20 0.54
DCPS Q96C86 1/20 0.54
P2RY12 Q9H244 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26212717 1.00 TGM2 (0.62) TGM2KRASFUT5NT5EP2RY6
SCHEMBL26201436 0.89 TGM2 (0.68) TGM2KRASFUT5NT5EP2RY6
SCHEMBL26204432 0.89 TGM2 (0.68) TGM2KRASFUT5NT5EP2RY6
SCHEMBL2033285 0.87 TGM2 (0.68) TGM2KRASFUT5NT5EP2RY6
SCHEMBL3187816 0.87 TGM2 (0.68) TGM2KRASFUT5NT5EP2RY6
SCHEMBL23149534 0.87 TGM2 (0.68) TGM2KRASFUT5NT5EP2RY6
SCHEMBL720115 0.87 TGM2 (0.68) TGM2KRASFUT5NT5EP2RY6
SCHEMBL20850065 0.87 TGM2 (0.68) TGM2KRASFUT5NT5EP2RY6
SCHEMBL29829660 0.87 TGM2 (0.68) TGM2KRASFUT5NT5EP2RY6
SCHEMBL15747229 0.87 TGM2 (0.68) TGM2KRASFUT5NT5EP2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4261217-A1 COMPOUND FOR RNA CAPPING AND APPLICATION OF COMPOUND Guangzhou Henovcom Bioscience Co., Ltd. (CN) 2023-10-18 EP disclosed