SCHEMBL26567853

SCHEMBL26567853

Cc1ccc(C(=C(c2ccccc2)c2ccccc2)c2ccc(N)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.56
CES2 O00748 1/20 0.54
CES1 P23141 1/20 0.54
CYP19A1 P11511 4/20 0.50
POLB P06746 2/20 0.48
LMNA P02545 2/20 0.48
NPC1 O15118 3/20 0.48
RAB9A P51151 3/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
CYP2D6 P10635 1/20 0.46
HIF1A Q16665 1/20 0.46
TEAD4 Q15561 1/20 0.45
ESR1 P03372 2/20 0.44
ESR2 Q92731 2/20 0.44
ALDH1A1 P00352 2/20 0.43
MAPT P10636 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
CTSL P07711 1/20 0.43
CTSB P07858 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12275074 1.00 ACHE (0.56) ACHECES2CES1CYP19A1POLB
SCHEMBL12275072 1.00 ACHE (0.56) ACHECES2CES1CYP19A1POLB
SCHEMBL30884727 1.00 ACHE (0.56) ACHECES2CES1CYP19A1POLB
SCHEMBL69743 0.89 CES2 (0.65) ACHECES2CES1POLBLMNA
SCHEMBL2566825 0.89 CYP19A1 (0.54) CES2CES1CYP19A1RAB9AMEN1
SCHEMBL69744 0.89 CES2 (0.65) ACHECES2CES1POLBLMNA
SCHEMBL15301748 0.89 CES2 (0.65) ACHECES2CES1POLBLMNA
SCHEMBL15326126 0.89 CYP19A1 (0.54) CES2CES1CYP19A1RAB9AMEN1
SCHEMBL11681167 0.89 CYP19A1 (0.54) CES2CES1CYP19A1RAB9AMEN1
SCHEMBL8906711 0.89 CYP19A1 (0.54) CES2CES1CYP19A1RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230327290-A1 SEPARATOR AND LITHIUM-ION BATTERY NINGDE AMPEREX TECHNOLOGY LIMITED (CN) 2023-10-12 US disclosed