Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.65 |
| ▸ | CES1 | P23141 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15301748 | 1.00 | CES2 (0.65) | CES2CES1NPC1RAB9AKMT2A | |
| SCHEMBL69743 | 1.00 | CES2 (0.65) | CES2CES1NPC1RAB9AKMT2A | |
| SCHEMBL28126874 | 0.91 | ESR1 (0.63) | CES2CES1NPC1RAB9AKMT2A | |
| SCHEMBL26567853 | 0.89 | ACHE (0.56) | CES2CES1NPC1RAB9AKMT2A | |
| SCHEMBL12275072 | 0.89 | ACHE (0.56) | CES2CES1NPC1RAB9AKMT2A | |
| SCHEMBL30884727 | 0.89 | ACHE (0.56) | CES2CES1NPC1RAB9AKMT2A | |
| SCHEMBL28548057 | 0.89 | ALDH1A1 (0.56) | CES2CES1NPC1RAB9AKMT2A | |
| SCHEMBL12275074 | 0.89 | ACHE (0.56) | CES2CES1NPC1RAB9AKMT2A | |
| SCHEMBL17923686 | 0.88 | ALDH1A1 (0.58) | CES2CES1NPC1RAB9AKMT2A | |
| SCHEMBL23332032 | 0.87 | ALDH1A1 (0.55) | CES2CES1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116496169-B | Amphiphilic tetraphenyl ethylene derivative, fluorescent sensing film, preparation method and application | 天津城建大学 | 2023-08-29 | — | — | CN | claimed |
| CN-116496169-A | Amphiphilic tetraphenyl ethylene derivative, fluorescent sensing film, preparation method and application | 天津城建大学 | 2023-07-28 | — | — | CN | claimed |
| CN-116496169-B | Amphiphilic tetraphenyl ethylene derivative, fluorescent sensing film, preparation method and application | 天津城建大学 | 2023-08-29 | — | — | CN | disclosed |
| CN-116496169-A | Amphiphilic tetraphenyl ethylene derivative, fluorescent sensing film, preparation method and application | 天津城建大学 | 2023-07-28 | — | — | CN | disclosed |
| US-9929363-B2 | Composition and synthesis of aggregation-induced emission materials | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2018-03-27 | — | — | US | disclosed |
| US-20160211470-A1 | COMPOSITION AND SYNTHESIS OF AGGREGATION-INDUCED EMISSION MATERIALS | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-07-21 | — | — | US | disclosed |
| US-9315465-B2 | Photostable AIE luminogens for specific mitochondrial imaging and its method of manufacturing thereof | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-04-19 | — | — | US | disclosed |
| US-9279806-B2 | Water-soluble AIE luminogens for monitoring and retardation of fibrillation of amyloid proteins | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-03-08 | — | — | US | disclosed |
| CN-103411961-B | A kind of fluorescence measuring critical micelle concentration of surfactant sensitive lights sonde method | SOUTHERN MEDICAL UNIVERSITY (CN) | 2016-01-06 | — | — | CN | disclosed |
| WO-2015018322-A1 | COMPOSITION AND SYNTHESIS OF AGGREGATION-INDUCED EMISSION MATERIALS | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-02-12 | — | — | WO | disclosed |
| US-20150031607-A1 | WATER-SOLUBLE AIE LUMINOGENS FOR MONITORING AND RETARDATION OF FIBRILLATION OF AMYLOID PROTEINS | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-01-29 | — | — | US | disclosed |
| US-20140212359-A1 | PHOTOSTABLE AIE LUMINOGENS FOR SPECIFIC MITOCHONDRIAL IMAGING AND ITS METHOD OF MANUFACTURING THEREOF | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2014-07-31 | — | — | US | disclosed |
| US-8679738-B2 | Water-soluble AIE luminogen for monitoring and retardation of amyloid fibrillation of insulin | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2014-03-25 | — | — | US | disclosed |
| CN-103411961-A | Sensitive fluorescent lighting probe method for determining CMC (critical micelle concentration) of surfactant | UNIV SOUTHERN MEDICAL | 2013-11-27 | — | — | CN | disclosed |
| US-20120172296-A1 | WATER-SOLUBLE AIE LUMINOGEN FOR MONITORING AND RETARDATION OF AMYLOID FIBRILLATION OF INSULIN | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (HK) | 2012-07-05 | — | — | US | disclosed |
| US-8129111-B2 | Fluorescent water-soluable conjugated polyene compounds that exhibit aggregation induced emission and methods of making and using same | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2012-03-06 | — | — | US | disclosed |
| US-7939613-B2 | Probes/sensors for biomacromolecules; films; cosmetics | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2011-05-10 | — | — | US | disclosed |
| US-20100009362-A1 | Fluorescent water-soluable conjugated polyene compounds that exhibit aggregation induced emission and methods of making and using same | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2010-01-14 | — | — | US | disclosed |
| US-20080220407-A1 | Fluorescent water-soluble conjugated polyene compounds that exhibit aggregation induced emission and methods of making and using same | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140212359-A1 | PHOTOSTABLE AIE LUMINOGENS FOR SPECIFIC MITOCHONDRIAL IMAGING AND ITS METHOD OF MANUFACTURING THEREOF | MAVS, AIFM1, GSR | CES2 4883/4885CES1 4823/4885NPC1 4354/4885 |
| US-20160211470-A1 | COMPOSITION AND SYNTHESIS OF AGGREGATION-INDUCED EMISSION MATERIALS | OCIAD2, ACIN1, JUND | CES2 3069/4885CES1 3934/4885NPC1 2765/4885 |
| US-20120172296-A1 | WATER-SOLUBLE AIE LUMINOGEN FOR MONITORING AND RETARDATION OF AMYLOID FIBRILLATION OF INSULIN | IAPP, IGF2BP1, IGF2BP2 | CES2 3923/4885CES1 3130/4885NPC1 4797/4885 |
| US-20080220407-A1 | Fluorescent water-soluble conjugated polyene compounds that exhibit aggregation induced emission and methods of making and using same | FUS, CD63, EPCAM | CES2 1125/4885CES1 2979/4885NPC1 3451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.