Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.51 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19472394 | 0.95 | KMT2A (0.63) | KMT2AKDM4ESMN1; SMN2MEN1TSHR | |
| SCHEMBL8947242 | 0.86 | KMT2A (0.67) | KMT2AMAPK1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL26579684 | 0.86 | MAPK1 (0.76) | KMT2AMAPK1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL5632141 | 0.85 | RAB9A (0.67) | KMT2AMAPK1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL16495499 | 0.83 | RXFP1 (0.56) | KMT2AKDM4ESMN1; SMN2MEN1TSHR | |
| SCHEMBL26566648 | 0.81 | KDM4E (0.61) | KDM4ESMN1; SMN2ALDH1A1HPGDPTPN1 | |
| Methylene Chloride SCHEMBL6847437 | 0.81 | RAB9A (0.62) | KMT2AMAPK1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL23099698 | 0.81 | NPC1 (0.67) | KMT2AKDM4ESMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL8718154 | 0.80 | EGLN1 (0.64) | KMT2AMAPK1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL14723435 | 0.80 | PTPN1 (0.58) | ALDH1A1HPGDPTPN1GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183405-A2 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2023-09-28 | — | — | WO | disclosed |