Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5632141 | 0.95 | RAB9A (0.67) | RAB9AMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL3961994 | 0.85 | GAA (0.59) | RAB9AMAPTMEN1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL9331679 | 0.84 | GAA (0.57) | RAB9AMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL8947242 | 0.83 | KMT2A (0.67) | RAB9AMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL29035299 | 0.83 | LMNA (0.55) | RAB9AMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL71818 | 0.82 | RAB9A (0.66) | RAB9AMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL26568778 | 0.82 | MAPK1 (0.80) | RAB9AMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL26568178 | 0.81 | KMT2A (0.59) | RAB9AMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL24224262 | 0.80 | KMT2A (0.59) | RAB9AMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL30838576 | 0.80 | KDM4E (0.62) | RAB9AMAPTMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389211-A1 | 3,7-DIAZYBICYCLO 3.3.1] FORMULATIONS AS ANTIARRHYTMIC COMPOUNDS | AstraZeneca AB (SE) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002083687-A1 | 3,7-DIAZYBICYCLO [3.3.1] FORMULATIONS AS ANTIARRHYTMIC COMPOUNDS | ASTRAZENECA AB (SE) | 2002-10-24 | — | — | WO | disclosed |