Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25506622 | 0.80 | PDE4A (0.32) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL4885770 | 0.77 | PDE4A (0.50) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL23869688 | 0.75 | HDAC1 (0.41) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL29483463 | 0.74 | MAPT (0.42) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL11077132 | 0.74 | RECQL (0.59) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL11077135 | 0.74 | RECQL (0.59) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL24285671 | 0.65 | GABRA1 (0.38) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL22969892 | 0.63 | HDAC1 (0.44) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL10891997 | 0.63 | HDAC1 (0.53) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL24855400 | 0.63 | RECQL (0.38) | MEN1KMT2AALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238439-A1 | HER3-BINDING ANTIBODY-DRUG CONJUGATE | Hummingbird Bioscience Pte. Ltd. (SG) | 2024-07-18 | — | — | US | disclosed |
| US-20230330245-A1 | ANTIBODY-EXATECAN CONJUGATES | SYNAFFIX B.V. (NL) | 2023-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240238439-A1 | HER3-BINDING ANTIBODY-DRUG CONJUGATE | ERBB3, EGFR, ERBB2 | MAPT 882/4885MEN1 557/4885KMT2A 797/4885 |
| US-20230330245-A1 | ANTIBODY-EXATECAN CONJUGATES | ERBB3, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, IL23R | MAPT 3039/4885MEN1 1881/4885KMT2A 1164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.