SCHEMBL26568476

SCHEMBL26568476

C[C@H]1O[C@@H](n2c[n+](C)c3c(=O)[nH]c(N)nc32)[C@H](O)[C@@H]1COCc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HINT1 P49773 2/20 0.41
EIF4E P06730 4/20 0.38
TLR7 Q9NYK1 1/20 0.37
HSPA5 P11021 1/20 0.37
GSK3A P49840 2/20 0.37
RPS6KA3 P51812 2/20 0.37
MAPK14 Q16539 2/20 0.37
PDE2A O00408 1/20 0.36
TAAR1 Q96RJ0 2/20 0.36
PNP P00491 1/20 0.35
ADORA2A P29274 1/20 0.34
ADORA2B P29275 1/20 0.34
NT5E P21589 1/20 0.34
HPRT1 P00492 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26201990 0.92 HINT1 (0.38) HINT1EIF4ETLR7HSPA5GSK3A
SCHEMBL26568603 0.88 HINT1 (0.40) HINT1EIF4ETLR7GSK3ARPS6KA3
SCHEMBL26568971 0.86 HINT1 (0.39) HINT1EIF4ETLR7GSK3ARPS6KA3
SCHEMBL26568912 0.86 HINT1 (0.39) HINT1EIF4ETLR7GSK3ARPS6KA3
SCHEMBL26571022 0.86 HINT1 (0.39) HINT1EIF4ETLR7GSK3ARPS6KA3
SCHEMBL26202070 0.86 HINT1 (0.39) HINT1EIF4ETLR7GSK3ARPS6KA3
SCHEMBL26566855 0.86 HINT1 (0.39) HINT1EIF4ETLR7GSK3ARPS6KA3
SCHEMBL26579734 0.86 HINT1 (0.57) HINT1EIF4ETLR7GSK3ARPS6KA3
SCHEMBL26213741 0.85 HINT1 (0.37) HINT1EIF4ETLR7GSK3ARPS6KA3
SCHEMBL26568972 0.85 HINT1 (0.38) HINT1EIF4ETLR7GSK3ARPS6KA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4261217-A1 COMPOUND FOR RNA CAPPING AND APPLICATION OF COMPOUND Guangzhou Henovcom Bioscience Co., Ltd. (CN) 2023-10-18 EP disclosed