Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.34 |
| ▸ | MMP2 | P08253 | 4/20 | 0.33 |
| ▸ | ANPEP | P15144 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8361030 | 0.66 | PTPN1 (0.31) | KMT2AALDH1A1 | |
| SCHEMBL14618066 | 0.61 | GRM4 (0.44) | KMT2AALDH1A1 | |
| SCHEMBL12367831 | 0.61 | CYP2C19 (0.52) | KMT2AALDH1A1 | |
| SCHEMBL15548316 | 0.60 | TSHR (0.36) | KMT2AALDH1A1 | |
| SCHEMBL21142881 | 0.60 | MMP2 (0.41) | MMP2ANPEPALDH1A1 | |
| SCHEMBL17611921 | 0.60 | APLNR (0.37) | KMT2AALDH1A1 | |
| SCHEMBL11503086 | 0.59 | KMT2A (0.31) | KMT2AALDH1A1 | |
| SCHEMBL21243947 | 0.59 | PTPN1 (0.31) | KMT2AALDH1A1 | |
| SCHEMBL12555452 | 0.59 | ALDH1A1 (0.31) | KMT2AALDH1A1 | |
| SCHEMBL4593503 | 0.59 | TP53 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183405-A2 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2023-09-28 | — | — | WO | disclosed |