Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22830016 | 1.00 | P2RX7 (0.53) | P2RX7 | |
| SCHEMBL22854881 | 1.00 | P2RX7 (0.53) | P2RX7 | |
| SCHEMBL26569056 | 1.00 | P2RX7 (0.53) | P2RX7 | |
| SCHEMBL26566525 | 0.82 | P2RX7 (0.38) | P2RX7 | |
| SCHEMBL16876420 | 0.79 | POLL (0.39) | — | |
| SCHEMBL22829933 | 0.76 | P2RX7 (0.43) | P2RX7 | |
| SCHEMBL22854651 | 0.74 | TBXAS1 (0.47) | P2RX7 | |
| SCHEMBL14720083 | 0.74 | TBXAS1 (0.47) | P2RX7 | |
| SCHEMBL3666423 | 0.74 | F12 (0.44) | — | |
| SCHEMBL1198594 | 0.74 | HDAC1 (0.39) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609868-B1 | TETRAHYDROQUINOLINE DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS | RAQUALIA PHARMA INC (JP) | 2023-10-18 | — | — | EP | disclosed |