Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | POLD1 | P28340 | 1/20 | 0.41 |
| ▸ | P2RY2 | P41231 | 13/20 | 0.37 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.37 |
| ▸ | TK1 | P04183 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25541253 | 0.86 | POLA1 (0.49) | POLA1POLBPOLD1P2RY2P2RY4 | |
| SCHEMBL18841240 | 0.85 | POLA1 (0.41) | POLA1POLBPOLD1P2RY2P2RY4 | |
| SCHEMBL25752104 | 0.81 | TK1 (0.41) | TK1 | |
| SCHEMBL17210946 | 0.78 | P2RY2 (0.53) | P2RY2P2RY4 | |
| SCHEMBL26479965 | 0.78 | POLB (0.68) | POLA1POLBPOLD1TK1 | |
| SCHEMBL20997626 | 0.78 | POLB (0.68) | POLA1POLBPOLD1TK1 | |
| SCHEMBL26571269 | 0.78 | POLB (0.68) | POLA1POLBPOLD1TK1 | |
| SCHEMBL26571270 | 0.78 | POLB (0.68) | POLA1POLBPOLD1TK1 | |
| SCHEMBL26420465 | 0.77 | POLA1 (0.34) | POLA1POLBTK1 | |
| SCHEMBL16158115 | 0.75 | TK1 (0.36) | TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230332197-A1 | NUCLEOSIDES AND NUCLEOTIDES WITH 3' VINYL BLOCKING GROUP | ILLUMINA, INC. | 2023-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230332197-A1 | NUCLEOSIDES AND NUCLEOTIDES WITH 3' VINYL BLOCKING GROUP | NT5C3B, NSUN2, DUT | POLA1 229/4885POLB 42/4885POLD1 269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.