Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.80 |
| ▸ | GAA | P10253 | 1/20 | 0.80 |
| ▸ | HPGD | P15428 | 4/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | RORC | P51449 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | KIF11 | P52732 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30571503 | 1.00 | KDM4E (0.80) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL26120061 | 0.85 | KDM4E (0.71) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL4727576 | 0.81 | KDM4E (0.78) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL13381591 | 0.80 | KDM4E (0.83) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL13697479 | 0.79 | KDM4E (0.69) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL71508 | 0.79 | KIF11 (0.82) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| Carbazole SCHEMBL11584093 | 0.76 | KIF11 (0.58) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL26570393 | 0.76 | BCAT1 (0.51) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL30209160 | 0.76 | KIF11 (0.60) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL22100411 | 0.76 | KIF11 (0.60) | KDM4EALDH1A1GAAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183405-A2 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2023-09-28 | — | — | WO | disclosed |