Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | MAPT | P10636 | 2/20 | 0.71 |
| ▸ | RAB9A | P51151 | 2/20 | 0.71 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.65 |
| ▸ | PARP1 | P09874 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | GABRP | O00591 | 1/20 | 0.61 |
| ▸ | GABRD | O14764 | 1/20 | 0.61 |
| ▸ | PDE5A | O76074 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28063129 | 0.92 | KIF11 (0.70) | KIF11KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL30522267 | 0.90 | KIF11 (1.00) | KIF11KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL2483277 | 0.90 | KIF11 (1.00) | KIF11KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL26119516 | 0.89 | KIF11 (0.71) | KIF11KDM4EALDH1A1MEN1KMT2A | |
| Carbazole SCHEMBL29280510 | 0.85 | KIF11 (0.73) | KIF11KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL30209160 | 0.84 | KIF11 (0.60) | KIF11KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL22100411 | 0.84 | KIF11 (0.60) | KIF11KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL30571577 | 0.83 | KIF11 (0.86) | KIF11KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL14376207 | 0.83 | KIF11 (0.86) | KIF11KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL4726935 | 0.83 | KDM4E (1.00) | KIF11KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113796380-A | Application of clausena lansium alkaloid and salt thereof in preparation of products for inhibiting phytophthora and/or ring rot activity | 江西农业大学 | 2021-12-17 | — | — | CN | claimed |
| WO-2020254672-A1 | SPATIAL CHARACTERISATION OF TARGET STRUCTURES IN A SAMPLE | THERYCELL GMBH (DE) | 2020-12-24 | — | — | WO | claimed |
| US-12319661-B2 | Polycyclic compound | EUTEC NEW MATERIALS TECHNOLOGY (SUZHOU) CO., LTD. (CN) | 2025-06-03 | — | — | US | disclosed |
| US-20250032448-A1 | COMPOUND FOR USE IN THE TREATMENT AND/OR PREVENTION OF PARASITIC MEDIATED DISEASES | KOH, Hwee Ling (SG) | 2025-01-30 | — | — | US | disclosed |
| CN-115745970-B | Polycyclic compound, preparation method and membrane | 江苏裕事达新材料科技有限责任公司 | 2024-12-13 | — | — | CN | disclosed |
| US-12144797-B2 | Compound for use in the treatment and/or prevention of parasitic mediated diseases | KOH, Hwee Ling (SG) | 2024-11-19 | — | — | US | disclosed |
| US-20230310373-A1 | METHODS FOR TREATING PULMONARY EMPHYSEMA USING SUBSTITUTED 2-AZA-BICYCLO[2.2.1]HEPTANE-3-CARBOXYLIC ACID (BENZYL-CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C | BOEHRINGER INGELHEIM INT (DE) | 2023-10-05 | — | — | US | disclosed |
| CN-111285853-B | Polycyclic compound | 江苏裕事达新材料科技有限责任公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-115745970-A | Polycyclic compound, preparation method and film | 江苏裕事达新材料科技有限责任公司 | 2023-03-07 | — | — | CN | disclosed |
| CN-113796380-B | Application of clausena lansium alkaloid and salt thereof in preparation of products for inhibiting phytophthora and/or ring rot activity | 江西农业大学 | 2022-06-10 | — | — | CN | disclosed |
| CN-113796380-B | Application of clausena lansium alkaloid and salt thereof in preparation of products for inhibiting phytophthora and/or ring rot activity | 江西农业大学 | 2022-06-10 | — | — | CN | disclosed |
| US-20100160323-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-06-24 | — | — | US | disclosed |
| WO-2009117676-A2 | NOVEL PIPERIDINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2009-09-24 | — | — | WO | disclosed |
| US-20090239810-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2009-09-24 | — | — | US | disclosed |
| US-20090227619-A1 | Harmine derivatives, intermediates used in their preparations, preparation processes and use therefo | XINJIANG HUASHIDAN PHARMACEUTICAL RESEARCH CO., LTD. (CN) | 2009-09-10 | — | — | US | disclosed |
| US-6713473-B1 | 6-CARBAMATE-1,2,3,4-TETRAHYDROCARBAZOLE DERIVATIVES; AFFINITY FOR NEUROPEPTIDE Y RECEPTORS | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-03-30 | — | — | US | disclosed |
| EP-1345898-A2 | TERACYCLIC CARBAZOLE DERIVATES AND THEIR USE AS SPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002050034-A2 | TETRACYCLIC CARBAZOLE DERIVATES AND THEIR USE AS SPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 2002-06-27 | — | — | WO | disclosed |
| EP-1184373-A1 | TRICYCLIC COMPOUNDS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-03-06 | — | — | EP | disclosed |
| WO-1990015061-A1 | NOVEL ALKALOIDS | THE UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) | 1990-12-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160323-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE | SCD, SCD5, FADS2 | KIF11 2975/4885KDM4E 434/4885ALDH1A1 969/4885 |
| US-20230310373-A1 | METHODS FOR TREATING PULMONARY EMPHYSEMA USING SUBSTITUTED 2-AZA-BICYCLO[2.2.1]HEPTANE-3-CARBOXYLIC ACID (BENZYL-CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C | CTSC, CTSG, CTSZ | KIF11 4354/4885KDM4E 1413/4885ALDH1A1 1189/4885 |
| US-12144797-B2 | Compound for use in the treatment and/or prevention of parasitic mediated diseases | ICMT, ALG3, PFN1 | KIF11 2974/4885KDM4E 2090/4885ALDH1A1 583/4885 |
| US-20090239810-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE | SCD, SCD5, FADS2 | KIF11 3230/4885KDM4E 375/4885ALDH1A1 784/4885 |
| US-20090227619-A1 | Harmine derivatives, intermediates used in their preparations, preparation processes and use therefo | TPH1, HTR1F, TPH2 | KIF11 3011/4885KDM4E 2869/4885ALDH1A1 324/4885 |
| US-12319661-B2 | Polycyclic compound | CUTA, CDH1, DSG1 | KIF11 3291/4885KDM4E 1855/4885ALDH1A1 878/4885 |
| US-20250032448-A1 | COMPOUND FOR USE IN THE TREATMENT AND/OR PREVENTION OF PARASITIC MEDIATED DISEASES | EPX, PKD2, MPO | KIF11 2575/4885KDM4E 2625/4885ALDH1A1 764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.