Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 14/20 | 0.81 |
| ▸ | PDE4B | Q07343 | 10/20 | 0.81 |
| ▸ | PDE4A | P27815 | 9/20 | 0.81 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.81 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.70 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piclamilast SCHEMBL26573 | 0.90 | PDE4D (1.00) | PDE4DPDE4BPDE4APDE4CCYP2B6 | |
| SCHEMBL7335911 | 0.89 | PDE4D (0.98) | PDE4DPDE4BPDE4APDE4CCYP2B6 | |
| SCHEMBL14456041 | 0.84 | PDE4D (0.88) | PDE4DPDE4BPDE4APDE4CCYP2B6 | |
| Filaminast SCHEMBL73843 | 0.84 | PDE4D (1.00) | PDE4DPDE4BPDE4APDE4CMAPK14 | |
| Filaminast SCHEMBL73844 | 0.84 | PDE4D (1.00) | PDE4DPDE4BPDE4APDE4CMAPK14 | |
| Filaminast SCHEMBL13986144 | 0.84 | PDE4D (1.00) | PDE4DPDE4BPDE4APDE4CMAPK14 | |
| Filaminast SCHEMBL29412441 | 0.84 | PDE4D (1.00) | PDE4DPDE4BPDE4APDE4CMAPK14 | |
| SCHEMBL7359687 | 0.83 | PDE4D (0.86) | PDE4DPDE4BPDE4APDE4CCYP2B6 | |
| SCHEMBL7336538 | 0.82 | PDE4D (0.84) | PDE4DPDE4BPDE4APDE4CCYP2B6 | |
| SCHEMBL7341113 | 0.82 | PDE4D (0.84) | PDE4DPDE4BPDE4APDE4CCYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2849741-A2 | OPHTHALMOLOGICAL VEHICLE SYSTEM FOR MEDICAMENTS, OPHTHALMOLOGICAL KIT AND USE OF AN OPHTHALMOLOGICAL COMPOSITION | F. Holzer GmbH (DE) | 2015-03-25 | — | — | EP | disclosed |
| WO-2013171203-A1 | FLUID DISPENSER CONTAINING AN OPHTHALMOLOGICAL COMPOSITION | F. HOLZER GMBH (DE) | 2013-11-21 | — | — | WO | disclosed |
| WO-2013171204-A2 | OPHTHALMOLOGICAL VEHICLE SYSTEM FOR MEDICAMENTS, OPHTHALMOLOGICAL KIT AND USE OF AN OPHTHALMOLOGICAL COMPOSITION | F. HOLZER GMBH (DE) | 2013-11-21 | — | — | WO | disclosed |
| EP-2664330-A1 | Composition and medication containing Omega 3 fatty acids and a glucosaminoglucan | F. Holzer GmbH (DE) | 2013-11-20 | — | — | EP | disclosed |
| EP-2664329-A1 | Ophthalmological vehicle system | F. Holzer GmbH (DE) | 2013-11-20 | — | — | EP | disclosed |
| EP-2635266-A1 | COMPOSITION AND DRUG CONTAINING OMEGA-3 FATTY ACIDS, AND A MODULATOR | F. Holzer GmbH (DE) | 2013-09-11 | — | — | EP | disclosed |
| WO-2012059158-A1 | COMPOSITION AND DRUG CONTAINING OMEGA-3 FATTY ACIDS, AND A MODULATOR | F. HOLZER GMBH (DE) | 2012-05-10 | — | — | WO | disclosed |