Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.54 |
| ▸ | NT5E | P21589 | 3/20 | 0.51 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30106724 | 1.00 | ADORA2A (0.54) | ADORA2AADORA1NT5ETLR7ADRB2 | |
| SCHEMBL693661 | 0.79 | NT5E (0.62) | ADORA2AADORA1NT5ETLR7ADRB2 | |
| SCHEMBL3300391 | 0.79 | BACE1 (0.66) | ADORA2AADORA1NT5ETLR7ADRB2 | |
| SCHEMBL28311336 | 0.79 | ADORA2A (0.55) | ADORA2AADORA1NT5ETLR7ADRB2 | |
| SCHEMBL11831263 | 0.79 | NT5E (0.45) | ADORA2AADORA1NT5EADRB2BACE1 | |
| SCHEMBL9493530 | 0.79 | NT5E (0.53) | ADORA2AADORA1NT5EADRB2BACE1 | |
| SCHEMBL14469360 | 0.78 | ADORA2A (0.54) | ADORA2AADORA1NT5ETLR7ADRB2 | |
| SCHEMBL29029738 | 0.78 | BACE1 (0.55) | ADORA2AADORA1NT5ETLR7ADRB2 | |
| SCHEMBL423741 | 0.78 | CYP1A2 (0.58) | ADORA2AADORA1TLR7ADRB2BACE1 | |
| SCHEMBL2425904 | 0.78 | ADORA2A (0.54) | ADORA2AADORA1NT5ETLR7ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119753869-A | Shape memory prestress anchor net material and preparation method thereof | 中煤科工开采研究院有限公司 | 2025-04-04 | — | — | CN | claimed |
| CN-119753869-A | Shape memory prestress anchor net material and preparation method thereof | 中煤科工开采研究院有限公司 | 2025-04-04 | — | — | CN | disclosed |
| CN-115108897-B | Preparation method of 4-ethoxy-1, 1-trifluoro-3-butene-2-ketone and derivative thereof | 帕潘纳(北京)科技有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-115108897-A | Preparation method of 4-ethoxy-1, 1, 1-trifluoro-3-butene-2-one and derivatives thereof | 帕潘纳(北京)科技有限公司 | 2022-09-27 | — | — | CN | disclosed |
| US-10391175-B2 | BET bromodomain inhibitors and therapeutic methods using the same | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2019-08-27 | — | — | US | disclosed |
| CN-105377851-B | BET bromodomain inhibitors and therapeutic methods using these inhibitors | 密执安州立大学董事会 | 2018-07-20 | — | — | CN | disclosed |
| CN-108285432-A | A kind of preparation method of quinoline | 湖南华腾制药有限公司 | 2018-07-17 | — | — | CN | disclosed |
| EP-2970312-B1 | BET BROMODOMAIN INHIBITORS AND THERAPEUTIC METHODS USING THE SAME | UNIV MICHIGAN REGENTS (US) | 2017-11-15 | — | — | EP | disclosed |
| EP-2970312-B1 | BET BROMODOMAIN INHIBITORS AND THERAPEUTIC METHODS USING THE SAME | UNIV MICHIGAN REGENTS (US) | 2017-11-15 | — | — | EP | disclosed |
| US-20170281773-A1 | BET BROMODOMAIN INHIBITORS AND THERAPEUTIC METHODS USING THE SAME | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2017-10-05 | — | — | US | disclosed |
| WO-2004087670-A1 | PROCESS FOR SYNTHESIS OF BIS-(SUBSTITUTED 4 QUINOLYL) DISULPHIDES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-10-14 | — | — | WO | disclosed |
| US-6777553-B1 | USING SUBSTITUTED-4-HALOQUINOLINES AND THE SODIUM, POTASSIUM OR AMMONIUM SALTS OF DITHIOCARBAMIC ACID WHICH AVOIDS THE HANDLING OF HAZARDOUS AND CORROSIVE CHLOROSULPHONIC ACID | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH | 2004-08-17 | — | — | US | disclosed |
| EP-1427408-A2 | CYCLIC HYDROXAMIC ACIDS AS INHIBITORS OF MATRIX METALLOPROTEINASES AND/OR TNF-$g(a) CONVERTING ENZYME (TACE) | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-06-16 | — | — | EP | disclosed |
| US-6740649-B2 | ANTIINFLAMMATORY AGENTS; OSTEOPOROSIS | BRISTOL-MYERS SQUIBB COMPANY | 2004-05-25 | — | — | US | disclosed |
| US-20030139388-A1 | Cyclic hydroxamic acids as inhibitors of matrix metalloproteinases and/or TNF-alpha converting enzyme (TACE) | BRISTOL-MYERS SQUIBB COMPANY (FORMERLY D/B/A DUPONT PHARMACEUTICALS COMPANY) | 2003-07-24 | — | — | US | disclosed |
| WO-2003024899-A2 | CYCLIC HYDROXAMIC ACIDS AS INHIBITORS OF MATRIX METALLOPROTEINASES AND/OR TNF-α CONVERTING ENZYME (TACE) | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-03-27 | — | — | WO | disclosed |
| CN-1138458-A | Treatment and prevention of prostatic cancer | LILLY CO ELI (US) | 1996-12-25 | — | — | CN | disclosed |
| WO-1996035422-A1 | METHODS FOR INHIBITING BONE LOSS | ELI LILLY AND COMPANY (US) | 1996-11-14 | — | — | WO | disclosed |
| US-4267333-A | Preparation of 2-trifluoromethyl cinchoninic acids | UNION CARBIDE AGRICULTURAL PRODUCTS COMPANY, INC. (US) | 1981-05-12 | — | — | US | disclosed |
| US-4251661-A | Preparation of 2-trifluoromethyl cinchoninic acids | UNION CARBIDE CORPORATION (US) | 1981-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139388-A1 | Cyclic hydroxamic acids as inhibitors of matrix metalloproteinases and/or TNF-alpha converting enzyme (TACE) | ADAMTS1, MMP1, ADAM17 | ADORA2A 4293/4885ADORA1 2212/4885NT5E 996/4885 |
| US-10391175-B2 | BET bromodomain inhibitors and therapeutic methods using the same | BRD4, BRDT, BRD3 | ADORA2A 4633/4885ADORA1 4711/4885NT5E 3798/4885 |
| US-20170281773-A1 | BET BROMODOMAIN INHIBITORS AND THERAPEUTIC METHODS USING THE SAME | BRD4, BRDT, BRD3 | ADORA2A 4633/4885ADORA1 4711/4885NT5E 3798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.