Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 7/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 8/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 8/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29079317 | 0.85 | HCRTR1 (0.40) | HCRTR1HCRTR2KMT2A | |
| SCHEMBL30614424 | 0.85 | HCRTR1 (0.40) | HCRTR1HCRTR2KMT2A | |
| SCHEMBL8872750 | 0.85 | EGLN2 (0.47) | APOBEC3AAPOBEC3GHPGDHCRTR1HCRTR2 | |
| SCHEMBL29265660 | 0.80 | APOBEC3A (0.45) | APOBEC3AAPOBEC3GHPGDHCRTR1HCRTR2 | |
| SCHEMBL10514737 | 0.80 | ALDH1A1 (0.50) | APOBEC3AAPOBEC3GHPGDHCRTR1HCRTR2 | |
| SCHEMBL10515422 | 0.78 | ALDH1A1 (0.48) | APOBEC3AAPOBEC3GHPGDHCRTR1HCRTR2 | |
| SCHEMBL17007538 | 0.77 | HCRTR1 (0.46) | APOBEC3AAPOBEC3GHPGDHCRTR1HCRTR2 | |
| SCHEMBL2893762 | 0.75 | L3MBTL1 (0.40) | HCRTR1HCRTR2KMT2AALDH1A1MAPT | |
| SCHEMBL5313640 | 0.74 | ALDH1A1 (0.45) | HPGDHCRTR1HCRTR2KMT2AALDH1A1 | |
| SCHEMBL29543454 | 0.74 | ALDH1A1 (0.45) | HPGDHCRTR1HCRTR2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010520-A1 | FUSED PHENYL AMIDO HETEROCYCLIC COMPOUNDS FOR THE PREVENTION AND TREATMENT OF GLUCOKINASE-MEDIATED DISEASES | Pfizer Products Incorporated (US) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007122482-A1 | FUSED PHENYL AMIDO HETEROCYCLIC COMPOUNDS FOR THE PREVENTION AND TREATMENT OF GLUCOKINASE-MEDIATED DISEASES | PFIZER PRODUCTS INC. (US) | 2007-11-01 | — | — | WO | disclosed |