Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26120142 | 0.83 | PKM (0.49) | PKMKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL26119458 | 0.83 | PKM (0.52) | PKMKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL17298034 | 0.80 | PKM (0.59) | PKMKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11919881 | 0.80 | KDM4E (0.59) | PKMKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL23415025 | 0.79 | ALPL (0.48) | PKMKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL23414771 | 0.77 | KDM4E (0.66) | PKMKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL19104683 | 0.77 | PKM (0.56) | PKMKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL19116406 | 0.77 | PKM (0.56) | PKMKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL17383700 | 0.77 | KDM4E (0.51) | KDM4EALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL26584232 | 0.77 | ALDH1A1 (0.51) | KDM4EALDH1A1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023180189-A1 | MPRO TARGETING ANTIVIRAL COMPOUNDS | EXSCIENTIA AI LIMITED (GB) | 2023-09-28 | — | — | WO | disclosed |