Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CDC25B | P30305 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LTC4S | Q16873 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL265593 | 0.93 | KDM4E (0.72) | ALDH1A1KDM4EPOLBGAAMEN1 | |
| SCHEMBL266168 | 0.91 | ALDH1A1 (0.66) | ALDH1A1KDM4EPOLBGAAMEN1 | |
| SCHEMBL265494 | 0.90 | SMN1; SMN2 (0.70) | ALDH1A1KDM4EPOLBGAAMEN1 | |
| SCHEMBL9314525 | 0.88 | MEN1 (0.52) | ALDH1A1KDM4EPOLBGAAMEN1 | |
| SCHEMBL264702 | 0.83 | ALDH1A1 (0.85) | ALDH1A1KDM4EPOLBGAAMEN1 | |
| SCHEMBL7475430 | 0.82 | GAA (0.71) | ALDH1A1KDM4EPOLBGAAMEN1 | |
| SCHEMBL17202297 | 0.81 | SMN1; SMN2 (0.64) | ALDH1A1KDM4EPOLBGAAMEN1 | |
| SCHEMBL11432389 | 0.81 | CDC25B (0.49) | ALDH1A1KDM4EPOLBGAAMEN1 | |
| SCHEMBL10933445 | 0.79 | ALDH1A1 (0.95) | ALDH1A1KDM4EPOLBGAAMEN1 | |
| SCHEMBL7489020 | 0.79 | MEN1 (0.65) | ALDH1A1KDM4EPOLBGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8134017-B1 | Compound and use thereof | RIKEN (JP) | 2012-03-13 | — | — | US | disclosed |