SCHEMBL265494

SCHEMBL265494

CCN(CC)c1ccc(C(=O)c2ccccc2C(=O)O)c(OC)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.70
L3MBTL1 Q9Y468 3/20 0.70
MEN1 O00255 2/20 0.70
KMT2A Q03164 2/20 0.70
ALDH1A1 P00352 8/20 0.54
KDM4E B2RXH2 3/20 0.54
GAA P10253 2/20 0.54
POLB P06746 1/20 0.54
CDC25B P30305 2/20 0.53
HPGD P15428 2/20 0.46
LMNA P02545 5/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
TSHR P16473 1/20 0.44
CYP2C19 P33261 1/20 0.44
LTC4S Q16873 1/20 0.44
MAPT P10636 4/20 0.44
MAPK1 P28482 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
GFER P55789 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17202297 0.91 SMN1; SMN2 (0.64) SMN1; SMN2L3MBTL1MEN1KMT2AALDH1A1
SCHEMBL265913 0.90 ALDH1A1 (0.61) SMN1; SMN2L3MBTL1MEN1KMT2AALDH1A1
SCHEMBL9416209 0.88 SMN1; SMN2 (0.68) SMN1; SMN2L3MBTL1MEN1KMT2AALDH1A1
SCHEMBL265593 0.88 KDM4E (0.72) SMN1; SMN2L3MBTL1MEN1KMT2AALDH1A1
SCHEMBL472333 0.87 ALDH1A1 (0.56) SMN1; SMN2L3MBTL1MEN1KMT2AALDH1A1
SCHEMBL9312635 0.87 MEN1 (0.54) SMN1; SMN2L3MBTL1MEN1KMT2AALDH1A1
SCHEMBL10597713 0.86 LMNA (0.56) SMN1; SMN2L3MBTL1MEN1KMT2AALDH1A1
SCHEMBL7489020 0.86 MEN1 (0.65) SMN1; SMN2L3MBTL1MEN1KMT2AALDH1A1
SCHEMBL266168 0.86 ALDH1A1 (0.66) SMN1; SMN2L3MBTL1MEN1KMT2AALDH1A1
SCHEMBL39206 0.82 KMT2A (1.00) SMN1; SMN2L3MBTL1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8134017-B1 Compound and use thereof RIKEN (JP) 2012-03-13 US disclosed
US-4940691-A Coloring phthalide compounds and recording materials using the compounds as coloring component RICOH COMPANY, LTD. (JP) 1990-07-10 US disclosed
US-4888322-A ANILINE AND AZO-METHINE DYES WITH GOOD COLORFASTNESS AND DENSITY FUJI PHOTO FILM CO., LTD. (JP) 1989-12-19 US disclosed
EP-0302529-A2 Recording material containing leuco dye FUJI PHOTO FILM CO., LTD. (JP) 1989-02-08 EP disclosed
US-4242513-A CHROMOGENS; PRESSURE AND HEAT SENSITIVE MARKING APPLETON PAPERS INC. (US) 1980-12-30 US disclosed
US-4119776-A Vinyl phthalide color formers NCR CORPORATION (US) 1978-10-10 US disclosed
US-4022771-A RECORD MATERIALS AND MARKING SYSTEMS NCR CORPORATION (US) 1977-05-10 US disclosed