SCHEMBL26597191

SCHEMBL26597191

COc1cccc(F)c1C(=O)Nc1ccc2nc(-c3ccc(F)cc3)[nH]c2c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 4/20 0.62
▸ MAPT P10636 4/20 0.57
▸ NR2E3 Q9Y5X4 2/20 0.56
▸ KDM4E B2RXH2 4/20 0.56
▸ ALDH1A1 P00352 3/20 0.56
▸ KDR P35968 2/20 0.52
▸ ABL1 P00519 1/20 0.52
▸ SRC P12931 1/20 0.52
▸ HPSE Q9Y251 3/20 0.52
▸ POLB P06746 2/20 0.52
▸ HPGD P15428 2/20 0.52
▸ SMN1; SMN2 Q16637 2/20 0.52
▸ APAF1 O14727 1/20 0.52
▸ PPARG P37231 1/20 0.52
▸ RECQL P46063 1/20 0.52
▸ SMAD3 P84022 1/20 0.52
▸ PTK2B Q14289 1/20 0.52
▸ ESR2 Q92731 1/20 0.52
▸ NCOR2 Q9Y618 1/20 0.52
▸ ATM Q13315 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30667669 1.00 KMT2A (0.62) KMT2AMAPTNR2E3KDM4EALDH1A1
SCHEMBL26753648 0.92 KMT2A (0.62) KMT2AMAPTNR2E3KDM4EALDH1A1
SCHEMBL31748608 0.86 NR2E3 (0.63) KMT2AMAPTNR2E3KDM4EALDH1A1
SCHEMBL26597196 0.86 NR2E3 (0.63) KMT2AMAPTNR2E3KDM4EALDH1A1
SCHEMBL31748729 0.84 NR2E3 (0.58) KMT2AMAPTNR2E3KDM4EALDH1A1
SCHEMBL26597202 0.84 NR2E3 (0.58) KMT2AMAPTNR2E3KDM4EALDH1A1
SCHEMBL30667676 0.84 NR2E3 (0.58) KMT2AMAPTNR2E3KDM4EALDH1A1
SCHEMBL31748600 0.80 NR2E3 (0.62) KMT2AMAPTNR2E3KDM4EALDH1A1
SCHEMBL26597175 0.80 NR2E3 (0.62) KMT2AMAPTNR2E3KDM4EALDH1A1
SCHEMBL31748482 0.79 MMP2 (0.72) KMT2AMAPTNR2E3KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250388551-A1 COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS UNIV PARIS CITE (FR) 2025-12-25 — — US disclosed
EP-4265246-A1 COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS Université Paris Cité (FR) 2023-10-25 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388551-A1 COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS CXCL10, CCR10, IL2 KMT2A 3012/4885MAPT 4593/4885NR2E3 2814/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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