Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.42 |
| ▸ | FOXM1 | Q08050 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2660289 | 1.00 | EPHX1 (0.42) | EPHX1HPGDTAAR1ALDH1A1SGMS2 | |
| SCHEMBL2658753 | 0.74 | EPHX1 (0.32) | EPHX1HPGDALDH1A1KMT2A | |
| SCHEMBL2658653 | 0.72 | SHBG (0.34) | EPHX1HPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL2659288 | 0.72 | SHBG (0.34) | EPHX1HPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL2659785 | 0.72 | SHBG (0.34) | EPHX1HPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL10942039 | 0.71 | TSHR (0.44) | — | |
| SCHEMBL4480785 | 0.70 | EPHX2 (0.49) | EPHX1HPGDTAAR1ALDH1A1SGMS2 | |
| SCHEMBL2660323 | 0.69 | CYP1A2 (0.35) | EPHX1ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL2659763 | 0.69 | CYP1A2 (0.35) | EPHX1ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL2659952 | 0.69 | CYP1A2 (0.35) | EPHX1ALDH1A1KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904466-A1 | DICYCLOALKYL UREA GLUCOKINASE ACTIVATORS | Novo Nordisk A/S (DK) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007006760-A1 | DICYCLOALKYL UREA GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2007-01-18 | — | — | WO | disclosed |