Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2659763 | 1.00 | CYP1A2 (0.35) | CYP1A2CYP2D6CYP2C19ALDH1A1EPHX1 | |
| SCHEMBL2660323 | 1.00 | CYP1A2 (0.35) | CYP1A2CYP2D6CYP2C19ALDH1A1EPHX1 | |
| SCHEMBL2658653 | 0.85 | SHBG (0.34) | ALDH1A1EPHX1KDM4EHSD17B10LMNA | |
| SCHEMBL2659785 | 0.85 | SHBG (0.34) | ALDH1A1EPHX1KDM4EHSD17B10LMNA | |
| SCHEMBL2659288 | 0.85 | SHBG (0.34) | ALDH1A1EPHX1KDM4EHSD17B10LMNA | |
| SCHEMBL2658545 | 0.84 | LMNA (0.36) | LMNAMAPTNPSR1 | |
| SCHEMBL2658753 | 0.76 | EPHX1 (0.32) | ALDH1A1EPHX1HSD17B10KMT2A | |
| SCHEMBL2660197 | 0.75 | MAPT (0.39) | ALDH1A1HSD17B10SIGMAR1MAPTMAPK1 | |
| SCHEMBL2658566 | 0.75 | MAPT (0.39) | ALDH1A1HSD17B10SIGMAR1MAPTMAPK1 | |
| SCHEMBL2659555 | 0.75 | MAPT (0.39) | ALDH1A1HSD17B10SIGMAR1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904466-A1 | DICYCLOALKYL UREA GLUCOKINASE ACTIVATORS | Novo Nordisk A/S (DK) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007006760-A1 | DICYCLOALKYL UREA GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2007-01-18 | — | — | WO | disclosed |