Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2659785 | 1.00 | SHBG (0.34) | SHBGALDH1A1MAPTL3MBTL1HSD17B10 | |
| SCHEMBL2658653 | 1.00 | SHBG (0.34) | SHBGALDH1A1MAPTL3MBTL1HSD17B10 | |
| SCHEMBL2660323 | 0.85 | CYP1A2 (0.35) | ALDH1A1MAPTL3MBTL1HSD17B10GAA | |
| SCHEMBL2659763 | 0.85 | CYP1A2 (0.35) | ALDH1A1MAPTL3MBTL1HSD17B10GAA | |
| SCHEMBL2659952 | 0.85 | CYP1A2 (0.35) | ALDH1A1MAPTL3MBTL1HSD17B10GAA | |
| SCHEMBL2658545 | 0.80 | LMNA (0.36) | MAPTNPSR1LMNA | |
| SCHEMBL2658753 | 0.79 | EPHX1 (0.32) | ALDH1A1HSD17B10EPHX1HPGDKMT2A | |
| SCHEMBL2660197 | 0.78 | MAPT (0.39) | ALDH1A1MAPTHSD17B10NPSR1 | |
| SCHEMBL2658566 | 0.78 | MAPT (0.39) | ALDH1A1MAPTHSD17B10NPSR1 | |
| SCHEMBL2659555 | 0.78 | MAPT (0.39) | ALDH1A1MAPTHSD17B10NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904466-A1 | DICYCLOALKYL UREA GLUCOKINASE ACTIVATORS | Novo Nordisk A/S (DK) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007006760-A1 | DICYCLOALKYL UREA GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2007-01-18 | — | — | WO | disclosed |