Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5C | P41229 | 2/20 | 0.45 |
| ▸ | KDM4B | O94953 | 1/20 | 0.45 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KDM6B | O15054 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.40 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.40 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30606793 | 1.00 | KDM5C (0.45) | KDM5CKDM4BKDM5BKDM4CKDM4E | |
| SCHEMBL29933114 | 0.78 | KDM1A (0.53) | KDM5CKDM4BKDM5BKDM4CKDM4E | |
| SCHEMBL1758494 | 0.77 | KDM4C (0.51) | KDM5CKDM4BKDM5BKDM4CKDM4E | |
| SCHEMBL2335933 | 0.77 | KDM4C (0.51) | KDM5CKDM4BKDM5BKDM4CKDM4E | |
| SCHEMBL4173650 | 0.76 | PROKR1 (0.48) | KDM5CKDM4BKDM5BMAP3K12OPRK1 | |
| SCHEMBL1035168 | 0.75 | NPY5R (0.41) | KDM5CKDM4BKDM5BKDM4CKDM4A | |
| SCHEMBL7038517 | 0.75 | KDM5C (0.69) | KDM5CKDM4BKDM5BKDM4CKDM4E | |
| SCHEMBL28200273 | 0.74 | KDM2B (0.52) | KDM5CKDM4BKDM5BKDM4CPIM1 | |
| SCHEMBL1846196 | 0.74 | SLC6A2 (0.40) | KDM5CKDM4BKDM5BDDB1CRBN | |
| SCHEMBL23720754 | 0.73 | KDM4B (0.46) | KDM5CKDM4BKDM5BKDM4CPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023202623-A1 | POLQ INHIBITOR COMPOUND AND USE THEREOF | 南京再明医药有限公司 | 2023-10-26 | — | — | WO | disclosed |