Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
| ▸ | JAK1 | P23458 | 2/20 | 0.40 |
| ▸ | TYK2 | P29597 | 2/20 | 0.40 |
| ▸ | JAK3 | P52333 | 2/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | KDM4B | O94953 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | PRKD1 | Q15139 | 4/20 | 0.38 |
| ▸ | PRKD2 | Q9BZL6 | 4/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1035168 | 0.90 | NPY5R (0.41) | SLC6A2SLC6A4SLC6A3JAK2JAK1 | |
| SCHEMBL1034197 | 0.82 | SCN9A (0.41) | SLC6A2SLC6A4SLC6A3MAPK14HTR1A | |
| SCHEMBL29050696 | 0.77 | JAK2 (0.44) | JAK2JAK1TYK2JAK3KDM4B | |
| SCHEMBL1847418 | 0.77 | PRKAA2 (0.44) | MAPK14KDM5B | |
| SCHEMBL5321644 | 0.74 | JAK2 (0.47) | SLC6A2SLC6A4SLC6A3JAK2JAK1 | |
| SCHEMBL26599370 | 0.74 | KDM5C (0.45) | KDM4BKDM5CKDM5BDDB1CRBN | |
| SCHEMBL30606793 | 0.74 | KDM5C (0.45) | KDM4BKDM5CKDM5BDDB1CRBN | |
| SCHEMBL6118725 | 0.72 | PRKD1 (0.45) | JAK2JAK1TYK2JAK3KDM4B | |
| SCHEMBL22648495 | 0.71 | JAK2 (0.45) | JAK2JAK1TYK2JAK3CDC7 | |
| Hydrochloric Acid SCHEMBL22635786 | 0.70 | JAK2 (0.44) | JAK2JAK1TYK2JAK3CDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2324010-A1 | INSECTICIDAL PHENYL- OR PYRIDYL-PIPERIDINE COMPOUNDS | Syngenta Participations AG (CH) | 2011-05-25 | — | — | EP | disclosed |