Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5C | P41229 | 6/20 | 0.69 |
| ▸ | KDM4B | O94953 | 3/20 | 0.69 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.69 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.53 |
| ▸ | KDM3A | Q9Y4C1 | 4/20 | 0.53 |
| ▸ | KDM4A | O75164 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | KDM6B | O15054 | 3/20 | 0.53 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.53 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 6/20 | 0.48 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
| ▸ | F7 | P08709 | 1/20 | 0.47 |
| ▸ | F3 | P13726 | 1/20 | 0.47 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18231524 | 0.92 | KDM5C (0.66) | KDM5CKDM4BKDM5BKDM2AKDM3A | |
| SCHEMBL902063 | 0.89 | KDM4E (0.72) | KDM5CKDM4BKDM5BKDM2AKDM3A | |
| SCHEMBL946431 | 0.85 | ASIC3 (0.55) | KDM5CKDM4BKDM5BKDM2AKDM3A | |
| SCHEMBL1592852 | 0.85 | KDM4B (0.58) | KDM5CKDM4BKDM5BKDM2AKDM3A | |
| SCHEMBL16033613 | 0.84 | KDM5C (0.54) | KDM5CKDM4BKDM5BKDM2AKDM3A | |
| SCHEMBL28907344 | 0.83 | KDM4B (0.56) | KDM5CKDM4BKDM5BKDM2AKDM3A | |
| SCHEMBL29932888 | 0.83 | MAP4K4 (0.55) | KDM5CKDM4BKDM5BMAP4K4PARP1 | |
| SCHEMBL31635775 | 0.82 | KDM4C (0.75) | KDM5CKDM4BKDM5BKDM2AKDM3A | |
| SCHEMBL31582735 | 0.82 | KDM5C (0.55) | KDM5CKDM4BKDM5BKDM2AKDM3A | |
| SCHEMBL1758188 | 0.82 | MAP4K4 (0.57) | KDM5CKDM4BKDM5BKDM2AKDM3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12612415-B2 | Stereoselective process for preparing substituted polycyclic pyridone | SHIONOGI & CO., LTD. (JP) | 2026-04-28 | — | — | US | disclosed |
| EP-3693373-B1 | STEREOSELECTIVE PROCESS FOR PREPARING SUBSTITUTED POLYCYCLIC PYRIDONE DERIVATIVES | SHIONOGI & CO (JP) | 2025-11-26 | — | — | EP | disclosed |
| CN-111386276-B | Stereoselective process for preparing substituted polycyclic pyridone derivatives | 盐野义制药株式会社 | 2023-06-23 | — | — | CN | disclosed |
| US-20230040262-A1 | STEREOSELECTIVE PROCESS FOR PREPARING SUBSTITUTED POLYCYCLIC PYRIDONE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2023-02-09 | — | — | US | disclosed |
| US-11286262-B2 | Stereoselective process for preparing substituted polycyclic pyridone derivatives | SHIONOGI & CO., LTD. (JP) | 2022-03-29 | — | — | US | disclosed |
| EP-3693373-A1 | METHOD FOR STEREOSELECTIVELY PRODUCING SUBSTITUTED POLYCYCLIC PYRIDONE DERIVATIVE | Shionogi&Co., Ltd. (JP) | 2020-08-12 | — | — | EP | disclosed |
| US-20200247818-A1 | STEREOSELECTIVE PROCESS FOR PREPARING SUBSTITUTED POLYCYCLIC PYRIDONE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2020-08-06 | — | — | US | disclosed |
| WO-2003055477-A1 | METHOD FOR THE TREATMENT OF MC RECEPTOR RELATED DISORDERS WITH A CHELATE AND/OR A CHELATOR | 7TM PHARMA A/S (DK) | 2003-07-10 | — | — | WO | disclosed |
| WO-2003003008-A1 | CHEMICAL LIBRARIES USEFUL FOR DRUG DISCOVERY PROCESSES | 7TM PHARMA A/S (DK) | 2003-01-09 | — | — | WO | disclosed |
| WO-2003003009-A1 | USE OF METAL-ION CHELATES IN VALIDATING BIOLOGICAL MOLECULES AS DRUG TARGETS IN TEST ANIMAL MODELS | 7TM PHARMA A/S (DK) | 2003-01-09 | — | — | WO | disclosed |
| US-5969150-A | FLUORESCENT COMPOUNDS FOR MEDICAL DIAGNOSIS, DRUGS AND LABELS OR FUNGICIDES AND VIRICIDES | THE ROCKEFELLER UNIVERSITY (US) | 1999-10-19 | — | — | US | disclosed |
| US-5064832-A | Bipyrimidine Compounds, Antitumor Agents | CIBA-GEIGY CORPORATION (US) | 1991-11-12 | — | — | US | disclosed |
| US-4968804-A | Bipyridine compounds | CIBA-GEIGY CORPORATION (US) | 1990-11-06 | — | — | US | disclosed |
| EP-0350448-A1 | Biaryl compounds | CIBA-GEIGY AG (CH) | 1990-01-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200247818-A1 | STEREOSELECTIVE PROCESS FOR PREPARING SUBSTITUTED POLYCYCLIC PYRIDONE DERIVATIVES | RNGTT, CPSF6, ENDOD1 | KDM5C 578/4885KDM4B 544/4885KDM5B 743/4885 |
| US-20230040262-A1 | STEREOSELECTIVE PROCESS FOR PREPARING SUBSTITUTED POLYCYCLIC PYRIDONE DERIVATIVES | RNGTT, CPSF6, RNASEL | KDM5C 575/4885KDM4B 549/4885KDM5B 746/4885 |
| US-11286262-B2 | Stereoselective process for preparing substituted polycyclic pyridone derivatives | RNGTT, CPSF6, ENDOD1 | KDM5C 578/4885KDM4B 544/4885KDM5B 743/4885 |
| US-12612415-B2 | Stereoselective process for preparing substituted polycyclic pyridone | POLR1A, RNASEH1, RNASEL | KDM5C 1564/4885KDM4B 1889/4885KDM5B 2119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.