Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28345587 | 1.00 | MAPT (0.45) | MAPTKMT2ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL29775198 | 1.00 | MAPT (0.45) | MAPTKMT2ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL26599496 | 1.00 | MAPT (0.45) | MAPTKMT2ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL28344994 | 0.84 | MEN1 (0.41) | MAPTKMT2ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL29775196 | 0.84 | ALDH1A1 (0.41) | MAPTKMT2ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL22340149 | 0.84 | ALDH1A1 (0.41) | MAPTKMT2ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL28345180 | 0.84 | ALDH1A1 (0.41) | MAPTKMT2ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL22340201 | 0.84 | ALDH1A1 (0.41) | MAPTKMT2ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL26601532 | 0.81 | KMT2A (0.49) | MAPTKMT2ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL8707255 | 0.78 | GAA (0.49) | MAPTKMT2ANPC1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11795149-B2 | Substituted indoline derivatives as dengue viral replication inhibitors | Janssen Pharmaceuticals, Inc. (US) | 2023-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11795149-B2 | Substituted indoline derivatives as dengue viral replication inhibitors | IDO1, INMT, IRF3 | MAPT 1807/4885KMT2A 1965/4885NPC1 1870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.