Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26670403 | 0.90 | SIGMAR1 (0.41) | SIGMAR1HPGDHRH4FAAHHRH3 | |
| Trifluoroacetic Acid SCHEMBL7814309 | 0.69 | PKM (0.49) | PKMSIGMAR1RAD52UBE2NL3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL3961759 | 0.69 | SIGMAR1 (0.61) | PKMSIGMAR1RAD52UBE2NL3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL8834402 | 0.69 | PKM (0.40) | PKMSIGMAR1RAD52UBE2NL3MBTL1 | |
| Methylpiperazine SCHEMBL2263099 | 0.69 | PKM (0.44) | PKMSIGMAR1RAD52UBE2NL3MBTL1 | |
| Methylpiperazine SCHEMBL2267453 | 0.69 | PKM (0.44) | PKMSIGMAR1RAD52UBE2NL3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL28163815 | 0.69 | PKM (0.48) | PKMSIGMAR1RAD52UBE2NL3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL2044334 | 0.68 | PKM (0.46) | PKMSIGMAR1RAD52UBE2NL3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL27832857 | 0.68 | SIGMAR1 (0.81) | PKMSIGMAR1RAD52UBE2NL3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL3956941 | 0.67 | CA2 (0.48) | PKMSIGMAR1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12454547-B2 | Steroidal compositions and methods of treating lipogenic cancers | Asteroid Therapeutics (US) | 2025-10-28 | — | — | US | disclosed |
| US-20230340011-A1 | STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS | Asteroid Therapeutics | 2023-10-26 | — | — | US | disclosed |
| WO-2023205801-A2 | STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS | Asteroid Therapeutics (US) | 2023-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12454547-B2 | Steroidal compositions and methods of treating lipogenic cancers | SREBF1, SREBF2, NR1H3 | PKM 2772/4885SIGMAR1 4011/4885RAD52 2352/4885 |
| US-20230340011-A1 | STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS | SREBF1, SREBF2, NR1H3 | PKM 2772/4885SIGMAR1 4011/4885RAD52 2352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.