Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | CNR2 | P34972 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NPY1R | P25929 | 1/20 | 0.50 |
| ▸ | NPY2R | P49146 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NOS1 | P29475 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29672461 | 1.00 | MAPT (0.61) | MAPTHPGDCA12CA9CNR2 | |
| SCHEMBL29697249 | 0.87 | PARP1 (0.51) | MAPTHPGDCA12CA9ALDH1A1 | |
| SCHEMBL588431 | 0.87 | PARP1 (0.51) | MAPTHPGDCA12CA9ALDH1A1 | |
| Tert-Butyl Formate SCHEMBL28007058 | 0.87 | MAPT (0.49) | MAPTHPGDCA12CA9CNR2 | |
| Quinoline SCHEMBL27625417 | 0.83 | MAPT (0.55) | MAPTHPGDCNR2ALDH1A1TDP1 | |
| SCHEMBL757425 | 0.81 | MAPT (0.63) | MAPTHPGDCA12CA9CNR2 | |
| SCHEMBL12193486 | 0.81 | MAPT (0.63) | MAPTHPGDCA12CA9CNR2 | |
| Sulfuric Acid SCHEMBL1405805 | 0.80 | PARP1 (0.46) | MAPTHPGDCA12CA9ALDH1A1 | |
| SCHEMBL3370857 | 0.80 | MAPT (0.61) | MAPTHPGDCA12CA9CNR2 | |
| SCHEMBL760760 | 0.80 | MAPT (0.61) | MAPTHPGDCA12CA9CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 416 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101429193-A | Process for producing 1-tetrahydropyran-3-methyl-5-amido indazole | UNIV NANCHANG HANGKONG (CN) | 2009-05-13 | — | — | CN | claimed |
| EP-0724193-B1 | Radiographic film developers containing ascorbic acid and thioether development accelerators | EASTMAN KODAK CO (US) | 1998-04-15 | — | — | EP | claimed |
| EP-0724193-A2 | Radiographic film developers containing ascorbic acid and thioether development accelerators | EASTMAN KODAK COMPANY (US) | 1996-07-31 | — | — | EP | claimed |
| US-5474879-A | Hydroquinone-free | EASTMAN KODAK COMPANY (US) | 1995-12-12 | — | — | US | claimed |
| EP-0666501-A2 | Hardening developer for silver halide photography and development method | EASTMAN KODAK COMPANY (US) | 1995-08-09 | — | — | EP | claimed |
| US-5389502-A | Black and white photography; hydroquinone and auxiliary developers, dialdehyde hardeners, antifoggants, sulfites, oligomeric carboxyl sequestering agents | EASTMAN KODAK COMPANY (US) | 1995-02-14 | — | — | US | claimed |
| US-4978603-A | Developing an emulsion layer containing a rhodium salt and a preferential grain size using a dihydroxy developer, a sulfite and an indazole compound | FUJI PHOTO FILM CO., LTD. (JP) | 1990-12-18 | — | — | US | claimed |
| US-12590071-B2 | Hydrazone derivative in which terminal amine group is substituted with aryl group or heteroaryl group, and use thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2026-03-31 | — | — | US | disclosed |
| US-20260034140-A1 | MODULATORS OF RHO-ASSOCIATED PROTEIN KINASE | REDX PHARMA LTD (GB) | 2026-02-05 | — | — | US | disclosed |
| US-12453734-B2 | Modulators of rho-associated protein kinase | REDX PHARMA LIMITED (GB) | 2025-10-28 | — | — | US | disclosed |
| EP-3676255-B1 | THERAPEUTIC INDAZOLES | RUTGERS THE STATE UNIV UNIV OF NEW JERSEY (US) | 2025-04-16 | — | — | EP | disclosed |
| CN-113727972-B | Novel hydrazone derivatives having terminal amine groups substituted with aryl or heteroaryl groups and use thereof | 韩国科学技术研究院 | 2024-12-27 | — | — | CN | disclosed |
| US-20240368132-A1 | ROCK2 INHIBITORS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2024-11-07 | — | — | US | disclosed |
| US-4810622-A | STABILITY | FUJI PHOTO FILM, CO. LTD. (JP) | 1989-03-07 | — | — | US | disclosed |
| EP-0238271-A2 | Silver halide photographic material and method of processing the same | KONICA CORPORATION (JP) | 1987-09-23 | — | — | EP | disclosed |
| US-4672025-A | BLACK AND WHITE PHOTOGRAPHIC DEVELOPER CONTAINING A CHELATING AGENT; AUTOMATIC PROCESSING | FUJI PHOTO FILM CO., LTD. (JP) | 1987-06-09 | — | — | US | disclosed |
| EP-0060118-B1 | STABLE PHOTOGRAPHIC DEVELOPING SOLUTION CONTAINING AN INDAZOLE ANTIFOGGANT AND A LIGNOSULFONATE | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1985-02-13 | — | — | EP | disclosed |
| EP-0060118-A1 | Stable photographic developing solution containing an indazole antifoggant and a lignosulfonate | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1982-09-15 | — | — | EP | disclosed |
| US-4323642-A | Stable photographic developers containing an indazole antifoggant and a lignosulfonate | EASTMAN KODAK COMPANY (US) | 1982-04-06 | — | — | US | disclosed |
| US-4221857-A | DEVELOPER COMPRISING SULFITE ION, A DIHYDROXYBENZENE, AND A HYDRAZIDE COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1980-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240368132-A1 | ROCK2 INHIBITORS AND USES THEREOF | ROCK2, ROCK1, RHOA | MAPT 1272/4885HPGD 947/4885CA12 1847/4885 |
| US-20260034140-A1 | MODULATORS OF RHO-ASSOCIATED PROTEIN KINASE | ROCK1, ROCK2, RHOA | MAPT 614/4885HPGD 2825/4885CA12 2973/4885 |
| US-12453734-B2 | Modulators of rho-associated protein kinase | ROCK2, ROCK1, RHOA | MAPT 909/4885HPGD 1635/4885CA12 4410/4885 |
| US-12590071-B2 | Hydrazone derivative in which terminal amine group is substituted with aryl group or heteroaryl group, and use thereof | ABL1, TH, CYP3A43 | MAPT 3633/4885HPGD 950/4885CA12 2979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.