Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 9/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.34 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.34 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.34 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3944507 | 0.84 | MAPT (0.44) | MAPTMAPK1HIF1AABCB1TDP1 | |
| SCHEMBL3944510 | 0.84 | MAPT (0.44) | MAPTMAPK1HIF1AABCB1TDP1 | |
| SCHEMBL14397682 | 0.84 | MAPT (0.44) | MAPTMAPK1HIF1AABCB1TDP1 | |
| SCHEMBL10425581 | 0.83 | MAPT (0.55) | MAPTMAPK1HIF1AABCB1TDP1 | |
| SCHEMBL25398613 | 0.74 | MAPT (0.41) | MAPTMAPK1HIF1AABCB1TDP1 | |
| SCHEMBL9815624 | 0.73 | LGALS3 (0.44) | MAPTABCB1LGALS9LGALS1LGALS3 | |
| SCHEMBL17863953 | 0.72 | MAPT (0.41) | MAPTMAPK1HIF1AABCB1TDP1 | |
| SCHEMBL17860797 | 0.72 | MAPT (0.41) | MAPTMAPK1HIF1AABCB1TDP1 | |
| SCHEMBL9815564 | 0.72 | MAPT (0.41) | MAPTABCB1TDP1LGALS9LGALS1 | |
| SCHEMBL14853753 | 0.71 | ABCB1 (0.45) | MAPTMAPK1HIF1AABCB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023178133-A9 | COMPOUNDS AND METHODS FOR TREATING DISEASE | ROME THERAPEUTICS, INC. (US) | 2023-10-26 | — | — | WO | disclosed |