Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | GNRHR | P30968 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31675858 | 1.00 | PDE10A (0.49) | PDE10ASMN1; SMN2NPC1TP53MAPT | |
| SCHEMBL31675879 | 0.90 | POLB (0.38) | PDE10ATP53RAB9ATSHRALDH1A1 | |
| SCHEMBL26601311 | 0.90 | POLB (0.38) | PDE10ATP53RAB9ATSHRALDH1A1 | |
| SCHEMBL26629775 | 0.87 | ALDH1A1 (0.41) | TP53RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL31461702 | 0.87 | ALDH1A1 (0.41) | TP53RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL31461697 | 0.87 | ALDH1A1 (0.41) | TP53RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL26630686 | 0.86 | EGFR (0.37) | SMN1; SMN2TP53MAPTRAB9AGAA | |
| SCHEMBL31571994 | 0.86 | KMT2A (0.41) | SMN1; SMN2TP53MAPTALDH1A1L3MBTL1 | |
| SCHEMBL31461693 | 0.84 | ALDH1A1 (0.44) | SMN1; SMN2TP53RAB9AALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL30623528 | 0.84 | EGFR (0.38) | SMN1; SMN2TP53MAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023205219-A1 | PROTEOLYSIS TARGETING CHIMERA (PROTAC) COMPOSITIONS USING UBIQUITIN CONJUGATING ENZYME LIGANDS | BERG LLC (US) | 2023-10-26 | — | — | WO | disclosed |
| WO-2023205219-A1 | PROTEOLYSIS TARGETING CHIMERA (PROTAC) COMPOSITIONS USING UBIQUITIN CONJUGATING ENZYME LIGANDS | BERG LLC (US) | 2023-10-26 | — | — | WO | disclosed |