Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | F2R | P25116 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | HCN1 | O60741 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26630686 | 0.93 | EGFR (0.37) | KMT2AMEN1MAPK1F2RALDH1A1 | |
| SCHEMBL26601311 | 0.92 | POLB (0.38) | L3MBTL1F2RALDH1A1HTTEGFR | |
| SCHEMBL31675879 | 0.92 | POLB (0.38) | L3MBTL1F2RALDH1A1HTTEGFR | |
| Trifluoroacetic Acid SCHEMBL26601324 | 0.90 | EGFR (0.38) | KMT2AMEN1F2RALDH1A1HTT | |
| Trifluoroacetic Acid SCHEMBL30623528 | 0.90 | EGFR (0.38) | KMT2AMEN1F2RALDH1A1HTT | |
| SCHEMBL31461697 | 0.88 | ALDH1A1 (0.41) | KMT2AMEN1L3MBTL1MAPK1F2R | |
| SCHEMBL31461702 | 0.88 | ALDH1A1 (0.41) | KMT2AMEN1L3MBTL1MAPK1F2R | |
| SCHEMBL26629775 | 0.88 | ALDH1A1 (0.41) | KMT2AMEN1L3MBTL1MAPK1F2R | |
| SCHEMBL31571990 | 0.87 | RORC (0.42) | L3MBTL1EGFRBTKPTGDR2PTGER4 | |
| SCHEMBL31675875 | 0.87 | ACACB (0.38) | ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025090847-A1 | ESTROGEN RECEPTOR DEGRADERS AND THEIR USE IN THE TREATMENT OF CANCER | BPGBIO, INC. (US) | 2025-05-01 | — | — | WO | disclosed |