Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 5/20 | 0.36 |
| ▸ | FDPS | P14324 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TAS2R14 | Q9NYV8 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CCR9 | P51686 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2668842 | 0.89 | KMT2A (0.39) | POLBALDH1A1KDM4EKMT2ANPC1 | |
| SCHEMBL2668751 | 0.80 | RAB9A (0.39) | CCR2ALDH1A1KMT2ARAB9AHSD17B10 | |
| SCHEMBL2660442 | 0.78 | CCR2 (0.35) | CCR2FDPSPOLBTAS2R14CCR9 | |
| SCHEMBL1653090 | 0.72 | TSHR (0.39) | CCR2FDPSALDH1A1KMT2ARAB9A | |
| SCHEMBL1653451 | 0.69 | RAB9A (0.38) | ALDH1A1KDM4EKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL2661943 | 0.69 | KMT2A (0.39) | CCR2POLBALDH1A1KMT2ANPC1 | |
| SCHEMBL2977393 | 0.69 | KMT2A (0.40) | ALDH1A1KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL2659895 | 0.69 | APEX1 (0.44) | ALDH1A1KDM4EKMT2ANPC1RAB9A | |
| SCHEMBL13312899 | 0.67 | CCR2 (0.37) | CCR2POLBALDH1A1KDM4EKMT2A | |
| SCHEMBL2668669 | 0.65 | CDK1 (0.44) | ALDH1A1KDM4EKMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074119-A1 | INDOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008050821-A1 | INDOLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-02 | — | — | WO | disclosed |