Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13312559 | 0.91 | LMNA (0.39) | RAB9ALMNAHPGDALDH1A1GAA | |
| SCHEMBL1653090 | 0.89 | TSHR (0.39) | RAB9ALMNAALDH1A1GAATSHR | |
| SCHEMBL1653451 | 0.89 | RAB9A (0.38) | RAB9ALMNAHPGDALDH1A1GAA | |
| SCHEMBL13222098 | 0.85 | ALDH1A1 (0.38) | RAB9ALMNAHPGDALDH1A1GAA | |
| SCHEMBL1653243 | 0.85 | POLB (0.40) | RAB9ALMNAHPGDALDH1A1GAA | |
| SCHEMBL13348480 | 0.83 | ALDH1A1 (0.36) | RAB9ALMNAHPGDALDH1A1GAA | |
| SCHEMBL1653085 | 0.81 | TSHR (0.39) | RAB9ALMNAHPGDALDH1A1GAA | |
| SCHEMBL2659384 | 0.80 | ALDH1A1 (0.48) | LMNAHPGDALDH1A1GAAKMT2A | |
| SCHEMBL2660445 | 0.80 | CCR2 (0.36) | RAB9AALDH1A1KMT2ACCR2SMN1; SMN2 | |
| SCHEMBL1653089 | 0.79 | TSHR (0.39) | RAB9ALMNAALDH1A1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2508524-A2 | Indole compound | Takeda Pharmaceutical Company Limited (JP) | 2012-10-10 | — | — | EP | disclosed |
| WO-2008050821-A1 | INDOLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-02 | — | — | WO | disclosed |