Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | ACLY | P53396 | 2/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2660266 | 0.90 | MEN1 (0.39) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL2659960 | 0.87 | KDM4E (0.45) | MEN1KMT2ANPC1RAB9AXDH | |
| SCHEMBL2659460 | 0.87 | MEN1 (0.34) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL2659185 | 0.87 | HPGD (0.40) | DAOMEN1KMT2AHRH4KDM4E | |
| SCHEMBL2659681 | 0.84 | SLC40A1 (0.37) | DAOKMT2AKDM4EMAPTGAA | |
| SCHEMBL2661084 | 0.82 | MCL1 (0.33) | DAOMEN1KMT2APOLBKDM4E | |
| SCHEMBL1653990 | 0.82 | KDM4E (0.48) | MEN1KMT2ANPC1KDM4EALDH1A1 | |
| SCHEMBL2659217 | 0.81 | IDO1 (0.39) | DAOKDM4EL3MBTL1ALDH1A1HPGD | |
| SCHEMBL2659861 | 0.79 | DAO (0.39) | DAOPIN1MEN1KMT2AL3MBTL1 | |
| SCHEMBL2659767 | 0.78 | PYGL (0.32) | MEN1KMT2APOLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074119-A1 | INDOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008050821-A1 | INDOLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-02 | — | — | WO | disclosed |