Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | EDNRB | P24530 | 2/20 | 0.32 |
| ▸ | EDNRA | P25101 | 2/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2660266 | 0.90 | MEN1 (0.39) | MEN1KMT2AHRH4NPC1POLB | |
| SCHEMBL2661534 | 0.87 | TUBB4A (0.36) | HRH4PKM | |
| SCHEMBL2660468 | 0.87 | DAO (0.39) | MEN1KMT2AHRH4NPC1POLB | |
| SCHEMBL2659960 | 0.83 | KDM4E (0.45) | MEN1KMT2ANPC1RAB9AXDH | |
| SCHEMBL2659039 | 0.82 | MEN1 (0.33) | MEN1KMT2APKMGAA | |
| SCHEMBL2660262 | 0.80 | PPIA (0.32) | HRH4 | |
| SCHEMBL2660619 | 0.79 | FBP1 (0.35) | MEN1KMT2APKMMAPTL3MBTL1 | |
| SCHEMBL2660294 | 0.77 | NSD2 (0.37) | MEN1KMT2AHRH4 | |
| SCHEMBL2659637 | 0.76 | PLA2G7 (0.36) | HRH4NPC1GAAMAPT | |
| SCHEMBL2660500 | 0.75 | KDM4E (0.36) | MEN1KMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074119-A1 | INDOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008050821-A1 | INDOLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-02 | — | — | WO | disclosed |