Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2603247 | 0.80 | ACHE (0.68) | ACHEALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL18133468 | 0.76 | HRH3 (0.49) | ALDH1A1KCNH2HRH3 | |
| SCHEMBL25945885 | 0.74 | ACHE (0.59) | ACHEALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL12261876 | 0.74 | ACHE (0.59) | ACHEALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL20233114 | 0.74 | ACHE (0.59) | ACHEALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL21431341 | 0.74 | RIPK1 (0.34) | — | |
| SCHEMBL1934947 | 0.74 | HPGD (0.55) | ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL24722046 | 0.73 | L3MBTL3 (0.67) | L3MBTL1L3MBTL3 | |
| SCHEMBL21508038 | 0.73 | POLB (0.50) | ALDH1A1KMT2AL3MBTL1NPC1MAPT | |
| SCHEMBL3731573 | 0.72 | HPGD (0.59) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11795159-B2 | Compounds for the treatment of SARS | PURDUE RESEARCH FOUNDATION (US) | 2023-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11795159-B2 | Compounds for the treatment of SARS | ACE2, ACE, SARS1 | ACHE 286/4885ALDH1A1 3093/4885NPSR1 854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.