Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.41 |
| ▸ | MAT2A | P31153 | 1/20 | 0.33 |
| ▸ | RORA | P35398 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | RORB | Q92753 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | CHUK | O15111 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5583119 | 0.80 | CCR2 (0.39) | MAT2ARORARORCRORBPKM | |
| SCHEMBL2661304 | 0.80 | ICMT (0.36) | SCN9ASCN5AMAT2APKMKIF11 | |
| SCHEMBL2660865 | 0.79 | SCN5A (0.39) | SCN9ASCN5ATBK1 | |
| SCHEMBL2662422 | 0.78 | CNR1 (0.39) | SCN9ASCN5ATBK1 | |
| SCHEMBL2660857 | 0.78 | KIF11 (0.39) | KIF11MAP2K4 | |
| SCHEMBL17038931 | 0.78 | PTGER4 (0.42) | PKMALDH1A1 | |
| SCHEMBL14380101 | 0.76 | CNR1 (0.47) | ALDH1A1 | |
| SCHEMBL30054489 | 0.75 | SCN9A (0.42) | SCN9AMAT2APKMKIF11ALDH1A1 | |
| SCHEMBL2634528 | 0.75 | SCN9A (0.42) | SCN9AMAT2APKMKIF11ALDH1A1 | |
| SCHEMBL17199372 | 0.75 | PTGER4 (0.38) | PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966152-A2 | GLUCOKINASE ACTIVATORS | Takeda Pharmaceutical Company Limited (JP) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007075847-A2 | GLUCOKINASE ACTIVATORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-07-05 | — | — | WO | disclosed |