Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.67 |
| ▸ | PIM1 | P11309 | 1/20 | 0.67 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.67 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.67 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.67 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.67 |
| ▸ | IDO1 | P14902 | 11/20 | 0.65 |
| ▸ | TDO2 | P48775 | 7/20 | 0.65 |
| ▸ | IDO2 | Q6ZQW0 | 7/20 | 0.65 |
| ▸ | APAF1 | O14727 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | CASP4 | P49662 | 2/20 | 0.41 |
| ▸ | CASP7 | P55210 | 2/20 | 0.41 |
| ▸ | CASP9 | P55211 | 2/20 | 0.41 |
| ▸ | CASP6 | P55212 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31382846 | 1.00 | CHEK1 (0.67) | CHEK1PIM1LIMK1TYRO3MAPK14 | |
| SCHEMBL31382863 | 0.89 | CHEK1 (0.77) | CHEK1PIM1LIMK1TYRO3MAPK14 | |
| SCHEMBL26614147 | 0.89 | CHEK1 (0.77) | CHEK1PIM1LIMK1TYRO3MAPK14 | |
| SCHEMBL31382864 | 0.83 | IDO1 (0.73) | CHEK1PIM1LIMK1TYRO3MAPK14 | |
| SCHEMBL26614143 | 0.83 | IDO1 (0.73) | CHEK1PIM1LIMK1TYRO3MAPK14 | |
| SCHEMBL26860827 | 0.82 | TDO2 (0.62) | CHEK1PIM1LIMK1TYRO3MAPK14 | |
| SCHEMBL26614108 | 0.81 | CHEK1 (0.78) | CHEK1PIM1LIMK1TYRO3MAPK14 | |
| SCHEMBL9221854 | 0.81 | IDO1 (0.73) | CHEK1PIM1LIMK1TYRO3MAPK14 | |
| SCHEMBL31382845 | 0.81 | CHEK1 (0.78) | CHEK1PIM1LIMK1TYRO3MAPK14 | |
| SCHEMBL26855996 | 0.81 | APAF1 (0.50) | CHEK1PIM1LIMK1TYRO3MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250171452-A1 | TRYPTANTHRIN DERIVATIVES AND USES THEREOF | VISCIENT BIO, INC. | 2025-05-29 | — | — | US | disclosed |
| EP-4514804-A1 | TRYPTANTHRIN DERIVATIVES AND USES THEREOF | Viscient Bio, Inc. (US) | 2025-03-05 | — | — | EP | disclosed |
| WO-2023211977-A1 | TRYPTANTHRIN DERIVATIVES AND USES THEREOF | VISCIENT BIO, INC. (US) | 2023-11-02 | — | — | WO | disclosed |
| WO-2023211977-A1 | TRYPTANTHRIN DERIVATIVES AND USES THEREOF | VISCIENT BIO, INC. (US) | 2023-11-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250171452-A1 | TRYPTANTHRIN DERIVATIVES AND USES THEREOF | IDO2, IDO1, TPSB2 | CHEK1 3580/4885PIM1 3187/4885LIMK1 3460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.