SCHEMBL26616596

SCHEMBL26616596

CO[Si](CCC(=O)OCCC#N)(OC)OC

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 1/20 0.33
ADRA1A P35348 1/20 0.33
MAPT P10636 1/20 0.32
BLM P54132 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
DGKA P23743 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26616751 0.86 ADRA2A (0.33) ADRA2AADRA1AMAPTBLMMEN1
SCHEMBL26616364 0.82 ZDHHC20 (0.32)
SCHEMBL26616699 0.81 MEN1 (0.33) MEN1KMT2A
SCHEMBL10011229 0.79 ADRA2A (0.44) ADRA2AADRA1AMAPTBLMMEN1
SCHEMBL14201372 0.78 DGKA (0.39) ADRA2AADRA1AMAPTBLMDGKA
SCHEMBL26616563 0.78 DGKA (0.44) ADRA2AADRA1AMAPTBLMDGKA
SCHEMBL10012540 0.77 ADRA2A (0.38) ADRA2AADRA1AMAPTBLMMEN1
SCHEMBL10009460 0.76 DGKA (0.45) ADRA2AADRA1AMAPTBLMMEN1
SCHEMBL9360984 0.75 DGKA (0.43) ADRA2AADRA1AMAPTBLMMEN1
SCHEMBL29028337 0.75 ADRA2A (0.46) ADRA2AADRA1AMAPTBLMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230340266-A1 SILICON-CONTAINING COMPOSITION AND METHOD FOR MANUFACTURING SEMICONDUCTOR SUBSTRATE JSR CORPORATION (JP) 2023-10-26 US disclosed