Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 18/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12917528 | 0.94 | KIF11 (0.46) | KIF11 | |
| SCHEMBL26616693 | 0.85 | ACHE (0.48) | ACHEKIF11 | |
| SCHEMBL26616674 | 0.84 | ALDH1A1 (0.38) | ACHE | |
| SCHEMBL16330568 | 0.84 | HDAC3 (0.40) | KIF11 | |
| SCHEMBL17493273 | 0.81 | CA14 (0.41) | KIF11 | |
| SCHEMBL14708941 | 0.79 | CA14 (0.45) | KIF11 | |
| SCHEMBL13753316 | 0.79 | KIF11 (0.43) | KIF11 | |
| SCHEMBL12660029 | 0.78 | KIF11 (0.40) | KIF11 | |
| SCHEMBL17546145 | 0.78 | KIF11 (0.40) | KIF11 | |
| SCHEMBL18291881 | 0.78 | CA14 (0.41) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11793861-B2 | PTH prodrugs | ASCENDIS PHARMA BONE DISEASES A/S (DK) | 2023-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11793861-B2 | PTH prodrugs | PTH1R, PTMS, PHPT1 | ACHE 3443/4885KIF11 4271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.