Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | CTSV | O60911 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ECE1 | P42892 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29535205 | 1.00 | ALDH1A1 (0.43) | ALDH1A1MAPK1MAPK14IDO1TSHR | |
| SCHEMBL26619622 | 1.00 | ALDH1A1 (0.43) | ALDH1A1MAPK1MAPK14IDO1TSHR | |
| SCHEMBL14453238 | 0.93 | IDO1 (0.43) | MAPK1IDO1DRD2CTSLCTSK | |
| SCHEMBL31757931 | 0.93 | IDO1 (0.43) | MAPK1IDO1DRD2CTSLCTSK | |
| SCHEMBL31757939 | 0.93 | IDO1 (0.43) | MAPK1IDO1DRD2CTSLCTSK | |
| SCHEMBL24593697 | 0.84 | MMP13 (0.38) | CTSKRAB9ASCN9ACTSS | |
| SCHEMBL22143906 | 0.84 | AAK1 (0.48) | CTSLCTSKRAB9ACTSS | |
| SCHEMBL22409744 | 0.84 | AAK1 (0.48) | CTSLCTSKRAB9ACTSS | |
| SCHEMBL22425331 | 0.84 | AAK1 (0.48) | CTSLCTSKRAB9ACTSS | |
| SCHEMBL22143651 | 0.84 | AAK1 (0.48) | CTSLCTSKRAB9ACTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023209519-A1 | CRYSTALLINE FORMS OF AN IL-17 INHIBITOR | NOVARTIS AG (CH) | 2023-11-02 | — | — | WO | disclosed |
| CN-116323596-A | Interleukin-17 inhibitors | 诺华股份有限公司 | 2023-06-23 | — | — | CN | disclosed |