Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 4/20 | 0.39 |
| ▸ | CDK2 | P24941 | 4/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 2/20 | 0.35 |
| ▸ | MYC | P01106 | 2/20 | 0.35 |
| ▸ | MAX | P61244 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1341940 | 0.84 | FFAR2 (0.44) | CCNE1CDK2CDK5LPAR1SMN1; SMN2 | |
| SCHEMBL1343187 | 0.82 | LPAR1 (0.39) | LPAR1SMN1; SMN2MEN1LMNAMAPT | |
| SCHEMBL1343072 | 0.81 | IDH2 (0.47) | LPAR1SMN1; SMN2MEN1MAPTKMT2A | |
| SCHEMBL1342982 | 0.81 | FBP1 (0.48) | LPAR1SMN1; SMN2 | |
| SCHEMBL1343242 | 0.81 | LPAR1 (0.37) | LPAR1SMN1; SMN2MEN1LMNAMAPT | |
| SCHEMBL1342455 | 0.81 | FFAR2 (0.43) | CCNE1CDK2CDK5LPAR1EP300 | |
| SCHEMBL1343714 | 0.80 | LPAR1 (0.38) | LPAR1SMN1; SMN2MEN1LMNAMAPT | |
| SCHEMBL2661997 | 0.80 | ALDH1A1 (0.36) | CCNE1CDK2CDK5LPAR1SMN1; SMN2 | |
| SCHEMBL1343463 | 0.80 | TP53 (0.46) | CCNE1CDK2CDK5LPAR1SMN1; SMN2 | |
| SCHEMBL6695225 | 0.79 | AURKA (0.39) | CDK2LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040122235-A1 | Aryl carbonyl derivatives as therapeutic agents | VTV THERAPEUTICS LLC | 2004-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040122235-A1 | Aryl carbonyl derivatives as therapeutic agents | GCK, GCKR, PDK2 | CCNE1 4257/4885CDK2 1019/4885CDK5 1122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.