Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | GCK | P35557 | 5/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HSPA5 | P11021 | 3/20 | 0.42 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HSPA2 | P54652 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2661212 | 0.88 | GCK (0.48) | LMNAXBP1GCKPKMHSPA5 | |
| SCHEMBL2654208 | 0.87 | GCK (0.47) | LMNAXBP1GCKPKMHSPA5 | |
| SCHEMBL2661654 | 0.87 | GCK (0.48) | LMNAXBP1GCKPKMHSPA5 | |
| SCHEMBL2651674 | 0.86 | LMNA (0.46) | LMNAXBP1GCKADORA2APKM | |
| SCHEMBL2652650 | 0.80 | LMNA (0.52) | LMNAGCKMEN1ALDH1A1KMT2A | |
| SCHEMBL2652704 | 0.80 | GCK (0.71) | GCK | |
| SCHEMBL2662041 | 0.79 | GCK (0.48) | LMNAGCKPKMHSPA5HSPA9 | |
| SCHEMBL2659242 | 0.78 | LMNA (0.49) | LMNAXBP1GCKPKMMEN1 | |
| SCHEMBL2652195 | 0.76 | NPC1 (0.54) | LMNAXBP1ADORA2APKMHSPA5 | |
| SCHEMBL2650213 | 0.76 | ADORA2A (0.49) | LMNAXBP1ADORA2AHSPA5HSPA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594867-A2 | PHENYLACETAMIDES AND THEIR USE AS GLUCOKINASE MODULATORS | Prosidion Limited (GB) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004072031-A2 | PHENYLACETAMIDES AND THEIR USE AS GLUCOKINASE MODULATORS | PROSIDION LIMITED (GB) | 2004-08-26 | — | — | WO | disclosed |