Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 4/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.43 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.43 |
| ▸ | HSPA9 | P38646 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.43 |
| ▸ | HSPA2 | P54652 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2652650 | 0.93 | LMNA (0.52) | GCKKCNK3KCNK9LMNAMAPT | |
| SCHEMBL2661212 | 0.88 | GCK (0.48) | GCKPKMHSPA5HSPA9LMNA | |
| SCHEMBL2661654 | 0.82 | GCK (0.48) | GCKPKMHSPA5HSPA9LMNA | |
| SCHEMBL2654208 | 0.80 | GCK (0.47) | GCKPKMHSPA5HSPA9LMNA | |
| SCHEMBL2651674 | 0.79 | LMNA (0.46) | GCKPKMHSPA5HSPA9LMNA | |
| SCHEMBL2662039 | 0.79 | LMNA (0.45) | GCKPKMHSPA5HSPA9LMNA | |
| SCHEMBL2662037 | 0.77 | GCK (0.67) | GCK | |
| SCHEMBL2652195 | 0.75 | NPC1 (0.54) | PKMKCNK3KCNK9HSPA5HSPA9 | |
| SCHEMBL2656217 | 0.71 | GCK (0.53) | GCKHSPA5HSPA9LMNANPC1 | |
| SCHEMBL2650185 | 0.71 | GCK (0.74) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594867-A2 | PHENYLACETAMIDES AND THEIR USE AS GLUCOKINASE MODULATORS | Prosidion Limited (GB) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004072031-A2 | PHENYLACETAMIDES AND THEIR USE AS GLUCOKINASE MODULATORS | PROSIDION LIMITED (GB) | 2004-08-26 | — | — | WO | disclosed |