Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410489 | 0.75 | NR1H4 (0.56) | HPGDHTT | |
| SCHEMBL449968 | 0.68 | HDAC3 (0.51) | HPGDHTT | |
| SCHEMBL2653898 | 0.67 | THRA (0.58) | — | |
| SCHEMBL14315097 | 0.67 | POLM (0.58) | — | |
| SCHEMBL29152244 | 0.66 | POLM (0.50) | HTT | |
| SCHEMBL24445761 | 0.66 | HPGD (0.47) | HPGD | |
| SCHEMBL14121014 | 0.66 | MAPK1 (0.54) | HPGDHTT | |
| SCHEMBL8676315 | 0.66 | KMT2A (0.57) | HPGDHTT | |
| SCHEMBL6405253 | 0.65 | KMT2A (0.59) | HPGDHTT | |
| SCHEMBL951698 | 0.65 | KMT2A (0.59) | HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010098948-A1 | GLUCAGON RECEPTOR ANTAGONIST COMPOUNDS, COMPOSITIONS CONTAININ SUCH COMPOUNDS AND METHODS OF USE | MERCK SHARP & DOHME CORP. (US) | 2010-09-02 | — | — | WO | disclosed |