Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | CTSG | P08311 | 1/20 | 0.43 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.43 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410787 | 0.83 | NR1H4 (0.62) | NR1H4KDM5BHPGDMAPK1PDCD1 | |
| SCHEMBL14121014 | 0.77 | MAPK1 (0.54) | HPGDMAPK1HTTPPARGPRSS1 | |
| SCHEMBL449968 | 0.77 | HDAC3 (0.51) | NR1H4HPGDMAPK1PDCD1CD274 | |
| SCHEMBL27375291 | 0.76 | CHRNB2 (0.54) | MAPK1PDCD1CD274HTTCHRNB2 | |
| SCHEMBL4831306 | 0.76 | NR1H4 (0.56) | NR1H4HPGDPDCD1CD274HTT | |
| SCHEMBL27890118 | 0.76 | NR1H4 (0.56) | NR1H4HTTALDH1A1GAAKDM4E | |
| SCHEMBL30394743 | 0.76 | HNF4A (0.58) | NR1H4HPGDMAPK1HTTALDH1A1 | |
| SCHEMBL4632581 | 0.76 | HNF4A (0.58) | NR1H4HPGDMAPK1HTTALDH1A1 | |
| SCHEMBL2662273 | 0.75 | CNR1 (0.42) | HPGDHTT | |
| SCHEMBL17799595 | 0.74 | HNF4A (0.56) | NR1H4HPGDMAPK1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922763-A | ANTICOAGULANT; CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1999-07-13 | — | — | US | disclosed |