Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GCGR | P47871 | 2/20 | 0.40 |
| ▸ | GIPR | P48546 | 2/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2657119 | 0.91 | NR1H4 (0.47) | MEN1KMT2AADRB2ADRB1CA12 | |
| SCHEMBL2654147 | 0.91 | FFAR1 (0.48) | MEN1KMT2AFFAR1FFAR4GCGR | |
| SCHEMBL2654579 | 0.90 | PPARD (0.43) | MEN1KMT2AADRB2ADRB1SPHK2 | |
| SCHEMBL2653054 | 0.89 | CA12 (0.42) | MEN1KMT2AADRB2ADRB1CA12 | |
| SCHEMBL2655056 | 0.89 | GCGR (0.47) | MEN1KMT2AROCK2ROCK1GCGR | |
| SCHEMBL2656241 | 0.89 | PPARD (0.42) | MEN1KMT2AROCK2ROCK1TRPV1 | |
| SCHEMBL2655101 | 0.88 | ESRRG (0.49) | MEN1KMT2AADRB2ADRB1CA12 | |
| SCHEMBL2653962 | 0.85 | MEN1 (0.58) | MEN1KMT2AROCK2ROCK1SPHK2 | |
| SCHEMBL2657509 | 0.85 | ROCK2 (0.41) | ROCK2ROCK1FFAR1TP53GCGR | |
| SCHEMBL2657152 | 0.85 | MEN1 (0.45) | MEN1KMT2ASPHK2MAOBMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758853-A1 | GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005123668-A1 | GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2005-12-29 | — | — | WO | disclosed |