SCHEMBL26622862

SCHEMBL26622862

CC[C@H]1O[C@@H](n2cnc3c(=O)[nH]c(N)nc32)[C@H](O)[C@@H]1CN

nearest known ligand 0.62

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ HINT1 P49773 5/20 0.62
▸ NT5E P21589 1/20 0.58
▸ GSK3A P49840 2/20 0.54
▸ RPS6KA3 P51812 2/20 0.54
▸ MAPK14 Q16539 2/20 0.54
▸ TGM2 P21980 1/20 0.54
▸ HPGD P15428 2/20 0.53
▸ STING1 Q86WV6 3/20 0.52
▸ PDE3B Q13370 1/20 0.52
▸ PDE3A Q14432 1/20 0.52
▸ PNP P00491 1/20 0.52
▸ TAAR1 Q96RJ0 1/20 0.51
▸ FUT5 Q11128 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17198483 0.91 HPGD (0.61) HINT1NT5EGSK3ARPS6KA3MAPK14
SCHEMBL19173745 0.89 HINT1 (0.72) HINT1NT5EGSK3ARPS6KA3MAPK14
SCHEMBL22268191 0.89 HINT1 (0.72) HINT1NT5EGSK3ARPS6KA3MAPK14
SCHEMBL19417780 0.89 HINT1 (0.72) HINT1NT5EGSK3ARPS6KA3MAPK14
SCHEMBL25706471 0.89 HINT1 (0.72) HINT1NT5EGSK3ARPS6KA3MAPK14
SCHEMBL14559271 0.89 HINT1 (0.72) HINT1NT5EGSK3ARPS6KA3MAPK14
SCHEMBL19204426 0.89 HINT1 (0.72) HINT1NT5EGSK3ARPS6KA3MAPK14
SCHEMBL784543 0.89 HINT1 (0.72) HINT1NT5EGSK3ARPS6KA3MAPK14
SCHEMBL26624281 0.89 HINT1 (0.65) HINT1NT5EGSK3ARPS6KA3MAPK14
SCHEMBL26623419 0.89 HINT1 (0.60) HINT1NT5EGSK3ARPS6KA3MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230340009-A1 COMPOUNDS FOR RNA CAPPING AND USES THEREOF GUANGZHOU HENOVCOM BIOSCIENCE CO., LTD. (CN) 2023-10-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230340009-A1 COMPOUNDS FOR RNA CAPPING AND USES THEREOF RNGTT, RNMT, NSUN2 HINT1 706/4885NT5E 803/4885GSK3A 4107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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