Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.71 |
| ▸ | MAPT | P10636 | 8/20 | 0.71 |
| ▸ | HPGD | P15428 | 2/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20774748 | 0.83 | MAPT (0.71) | ALDH1A1MAPTHPGDPOLBGAA | |
| SCHEMBL28033893 | 0.82 | ALDH1A1 (1.00) | ALDH1A1MAPTHPGDGAAMEN1 | |
| SCHEMBL5455602 | 0.77 | MAPT (0.83) | ALDH1A1MAPTGAAIDO1MAOA | |
| SCHEMBL8956372 | 0.77 | MAPT (0.83) | ALDH1A1MAPTGAAIDO1MAOA | |
| SCHEMBL20774650 | 0.76 | ALDH1A1 (0.61) | ALDH1A1MAPTHPGDGAAMAOA | |
| SCHEMBL26622953 | 0.72 | ALDH1A1 (0.67) | ALDH1A1MAPTHPGDPOLBGAA | |
| SCHEMBL8446661 | 0.71 | POLB (0.55) | ALDH1A1MAPTPOLBGAAMEN1 | |
| SCHEMBL17131909 | 0.71 | ALDH1A1 (0.68) | ALDH1A1MAPTHPGDPOLBGAA | |
| SCHEMBL5137359 | 0.70 | ALDH1A1 (1.00) | ALDH1A1MAPTGAAIDO1MAOA | |
| SCHEMBL9036606 | 0.70 | IDO1 (1.00) | ALDH1A1MAPTIDO1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3679037-B1 | NEW 5-AMINOTETRAZOLE DERIVATIVES WITH ANTIBACTERIAL AND ANTIFUNGAL ACTIVITY | UNIV WARSZAWSKI MEDYCZNY (PL) | 2023-11-08 | — | — | EP | disclosed |