Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 1.00 |
| ▸ | MAPT | P10636 | 7/20 | 1.00 |
| ▸ | MAOA | P21397 | 3/20 | 1.00 |
| ▸ | MAOB | P27338 | 3/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.74 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.69 |
| ▸ | MEN1 | O00255 | 7/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5455602 | 0.91 | MAPT (0.83) | ALDH1A1MAPTMAOAMAOBCYP3A4 | |
| SCHEMBL8956372 | 0.91 | MAPT (0.83) | ALDH1A1MAPTMAOAMAOBCYP3A4 | |
| SCHEMBL8956322 | 0.89 | ALDH1A1 (0.94) | ALDH1A1MAPTMAOAMAOBCYP3A4 | |
| SCHEMBL132620 | 0.86 | ALDH1A1 (1.00) | ALDH1A1MAPTMAOAMAOBCYP3A4 | |
| SCHEMBL11067809 | 0.84 | MEN1 (0.83) | ALDH1A1MAPTMAOAMAOBCYP3A4 | |
| SCHEMBL9470190 | 0.84 | ALDH1A1 (0.94) | ALDH1A1MAPTMAOAMAOBCYP3A4 | |
| SCHEMBL9243020 | 0.82 | ALDH1A1 (0.81) | ALDH1A1MAPTMAOAMAOBCYP3A4 | |
| SCHEMBL16566477 | 0.82 | KMT2A (1.00) | ALDH1A1MAPTMAOAMAOBCYP3A4 | |
| SCHEMBL9470151 | 0.81 | ALDH1A1 (0.67) | ALDH1A1MAPTMAOAMAOBCYP3A4 | |
| SCHEMBL11060530 | 0.81 | CNR1 (0.70) | ALDH1A1MAPTMAOAMAOBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5236633-A | Blend of transparent polymer, thiourea and copper compounds | JUJO PAPER CO., LTD. (JP) | 1993-08-17 | — | — | US | claimed |
| US-4264710-A | AN ETHYLENICALLY UNSATURATED COMPOUND, AND A PHOTOPOLYMERIZATION INIATOR | FUJI PHOTO FILM CO., LTD. (JP) | 1981-04-28 | — | — | US | claimed |
| US-20150080580-A1 | THIOUREA DERIVATIVES AS a-CHYMOTRYPSIN INHIBITORS | RAHMAN ATTA-UR (PK) | 2015-03-19 | — | — | US | disclosed |
| US-20150080580-A1 | THIOUREA DERIVATIVES AS a-CHYMOTRYPSIN INHIBITORS | RAHMAN ATTA-UR (PK) | 2015-03-19 | — | — | US | disclosed |
| US-20080227895-A1 | Fire retardant vinyl chloride-based resin composition and molded article thereof | MITSUBISHI PLASTICS, INC. (JP) | 2008-09-18 | — | — | US | disclosed |
| US-20060014874-A1 | Flame-resistant vinyl chlorride based resin composition and formed product therefrom | MITSUBISHI PLASTICS, INC. (JP) | 2006-01-19 | — | — | US | disclosed |
| US-5514740-A | SHEET OR FILM HAVING CUPRIC SULFIDE DISPERSED THEREIN | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-07 | — | — | US | disclosed |
| US-5393443-A | Hard-coating, heat-absorbing composition and heat-shielding substance | JUJO PAPER CO., LTD. (JP) | 1995-02-28 | — | — | US | disclosed |
| US-4461821-A | Photoconductive compositions and electrophotographic photosensitive materials comprising an organic photoconductor and a thiourea compound | FUJI PHOTO FILM CO., LTD. (JP) | 1984-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150080580-A1 | THIOUREA DERIVATIVES AS a-CHYMOTRYPSIN INHIBITORS | SERPINB1, CTRL, RNASE1 | ALDH1A1 1629/4885MAPT 2757/4885MAOA 2119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.